Can a laser drill through the Heart's hardest blockages?

NCT ID NCT07743528

First seen Aug 04, 2026 · Last updated Aug 05, 2026 · Updated 1 time

Summary

This trial tests a new device called the Angimis Atherectomy System, which uses laser energy to break up plaque in coronary arteries that are too narrow or hardened for standard balloon or stent procedures. The study enrolls adults with coronary artery disease who have at least one lesion that cannot be crossed or expanded with conventional tools. The main goal is to see if the device can successfully restore blood flow, with follow-up checks for safety and complications over a year.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Angimis Atherectomy System (a device that uses laser energy to remove plaque from coronary arteries)
What this could lead to
If successful, this device could offer a new way to open coronary arteries that are too hard or blocked for standard balloon or stent treatment, potentially reducing the need for more invasive surgery.
What could go wrong
This is an early-stage, single-arm study without a comparison group, so results may not be definitive. Risks include procedural complications such as vessel perforation, dissection, or stent thrombosis.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

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