Gel shield could spare prostate cancer patients from radiation damage

NCT ID NCT06451614

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tests a gel called SpaceIT that is placed between the prostate and rectum before radiation therapy for prostate cancer. The gel acts as a spacer to reduce radiation reaching the rectum, potentially lowering side effects. About 230 adults with low- to intermediate-risk prostate cancer will receive the gel and then undergo standard external beam radiation. The goal is to see if the gel safely reduces rectal radiation exposure.

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Conditions

The condition(s) this trial relates to.

prostate cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Associated Urological Specialists

    Chicago Ridge, Illinois, 60415, United States

  • Baptist Hospital of Miami

    Miami, Florida, 33176, United States

  • Emory University Hospital

    Atlanta, Georgia, 30308, United States

  • Evergreen Hospital Medical Center

    Kirkland, Washington, 98034, United States

  • Gibbs Cancer Center and Research Institute

    Greer, South Carolina, 29650, United States

  • Houston Metro Urology

    Houston, Texas, 77027, United States

  • Integrated Medical Professionals

    New York, New York, 10016, United States

  • Memorial Sloan Kettering

    New York, New York, 10065, United States

  • Mercy Cancer Center Bon Secours Mercy Healt

    Elyria, Ohio, 44035, United States

  • MidLantic Urology

    Bala-Cynwyd, Pennsylvania, 19004, United States

  • Midtown Urology Associates

    Austin, Texas, 78705, United States

  • Orange County Urology Associates

    Laguna Hills, California, 92653, United States

  • Orlando Health Cancer Institute

    Orlando, Florida, 32806, United States

  • Perelman Center for Advanced Medicine

    Philadelphia, Pennsylvania, 19104, United States

  • Perlmutter Cancer Center - NYU Langone

    New York, New York, 10016, United States

  • Princess Margaret Cancer Centre

    Toronto, Ontario, M5G 2M9, Canada

  • Rio Grande Urology

    El Paso, Texas, 79912, United States

  • Ronald Reagan UCLA Medical Center

    Los Angeles, California, 90095, United States

  • Springfield Clinic, LLC

    Springfield, Illinois, 62701, United States

  • Sunnybrook Health Sciences Centre-Hospital

    Toronto, Ontario, M4N 3M5, Canada

  • The Ottawa Hospital - General Campus

    Ottawa, Ontario, K1H 8L6, Canada

  • University Hospitals of Cleveland-Hospital

    Cleveland, Ohio, 44106, United States

  • University of Kansas Hospital

    Kansas City, Kansas, 66160, United States

  • University of Texas, Southwestern Medical Center

    Dallas, Texas, 75390, United States

  • University of Washington Medical Center-Hospital

    Seattle, Washington, 98195, United States

  • UroPartners

    Glenview, Illinois, 60026, United States