New heart device aims to zap away irregular rhythm

NCT ID NCT05501873

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is tracking over 1,100 people with atrial fibrillation who are treated with the FARAPULSE system, a device that uses electrical pulses to destroy tiny areas of heart tissue causing the irregular rhythm. The goal is to see how well it works and how safe it is in everyday hospital use. Researchers will check if patients stay in normal rhythm for at least 12 months after the procedure.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

FARAPULSE Pulsed Field Ablation system (a device that uses electrical pulses to destroy abnormal heart tissue)

What this could lead to

If successful, this could confirm that pulsed field ablation is a safe and effective way to treat atrial fibrillation and restore normal heart rhythm.

What could go wrong

This is an observational registry, not a controlled trial, so results may be less definitive. Risks include device- or procedure-related serious side effects, and long-term benefits are still being studied.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

atrial fibrillation

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • AZ Sint Jan Hospital

    Bruges, Belgium

  • Allgemeines Krankenhaus AKH

    Vienna, Austria

  • Az. Osp. Lancisi-Hospital

    Ancona, Italy

  • CHR de la Citadelle

    Liège, Belgium

  • CHU Grenoble

    Grenoble, France

  • Casa Di Cura 'Montevergine' S.P.A.

    Mercogliano, Italy

  • Catharina Ziekenhuis

    Eindhoven, Netherlands

  • Centre Cardiologique du Nord

    Saint-Denis, France

  • Centro Especial Ramon y Cajal

    Madrid, Spain

  • Clinica Universidad de Navarra

    Pamplona, Spain

  • Clinique Ambroise Pare-Hospital

    Neuilly, France

  • Clinique Pasteur Toulouse

    Toulouse, France

  • Facharztzentrum Dresden-Neustadt Betriebsgesellschaft mbH

    Dresden, Germany

  • Fiona Stanley Hospital

    Murdoch, Australia

  • Georg-August-Universitaet Goettingen

    Göttingen, Germany

  • Hartcentrum Hasselt Jessa Ziekenhuis Campus Virga Jesse

    Hasselt, Belgium

  • Henry Dunant hospital

    Athens, Greece

  • Hopital Prive du Confluent SAS

    Nantes, France

  • Hopital Saint Philibert-Hospital

    Lomme, France

  • Hospital Clinico Universitario Lozano Blesa

    Zaragoza, Spain

  • Hospital Universitario La Fe

    Valencia, Spain

  • Hospital de Santa Cruz

    Carnaxide, Portugal

  • Institut Jantung Negara

    Kuala Lumpur, Malaysia

  • John Hunter Hospital

    Newcastle, Australia

  • King Fahd Armed Forces Hospital

    Jeddah, Saudi Arabia

  • Liverpool Heart & Chest Hospital

    Liverpool, United Kingdom

  • Mater Private Hospital

    Dublin, Ireland

  • Nemocnice Ceske Budejovice a.s.

    České Budějovice, Czechia

  • Neuron Medical in Brno

    Brno, Czechia

  • Onassis Cardiac Surgery Center

    Athens, Greece

  • Ospedale Isola Tiberina Gemelli Isola

    Roma, Italy

  • Ospedale Rivoli

    Rivoli, Italy

  • Ospedale San Bortolo de Vicenza

    Vicenza, Italy

  • Prince Charles Hospital

    Brisbane, Australia

  • Prince of Wales Hospital

    Hong Kong, Hong Kong

  • Princesse Grace

    Monaco, Monaco

  • Queen Mary Hospital

    Hong Kong, Hong Kong

  • Royal Papworth Hospital

    Cambridge, United Kingdom

  • Semmelweis University

    Budapest, Hungary

  • St Georg Asklepios

    Hamburg, Germany

  • St. Antonius Ziekenhuis

    Nieuwegein, Netherlands

  • Staedisches Klinikum Karlsruhe

    Karlsruhe, Germany

  • Tays Heart Hospital

    Tampere, Finland

  • Tel Aviv Sourasky Medical Center

    Tel Aviv, Israel

  • Universitaetsklinikum Aachen (UKA)

    Aachen, Germany

  • Universitaetsklinikum Heidelberg

    Heidelberg, Germany

  • University Hospital of Muenster

    Münster, Germany

  • Uniwersyteckie Centrum Kliniczne Warszawskiego Uniwersytetu Medycznego

    Warsaw, Poland