New hope for weight loss after GLP-1 failure: stomach procedure vs. diet and exercise

NCT ID NCT07190794

Recruiting now Disease control Sponsor: Boston Scientific Corporation Source: ClinicalTrials.gov ↗

First seen Nov 01, 2025 · Last updated Apr 25, 2026 · Updated 28 times

Summary

This study looks at 150 adults with obesity who stopped taking popular weight-loss drugs (like Wegovy or Mounjaro) because of side effects or not losing enough weight. It compares two options: a minimally invasive procedure called endoscopic sleeve gastroplasty (ESG) that reduces stomach size, versus standard lifestyle changes like diet and exercise. The goal is to see which approach leads to more weight loss after one year.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

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Contact

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Locations

Bariendo
RECRUITING

Miami, Florida, 33179, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Brigham & Women's Hospital
NOT_YET_RECRUITING

Boston, Massachusetts, 02115, United States

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West Virginia University
NOT_YET_RECRUITING

Morgantown, West Virginia, 26506, United States

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Conditions

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OBESITY