HEART FAILURE WITH REDUCED EJECTION FRACTION
Clinical trials for HEART FAILURE WITH REDUCED EJECTION FRACTION explained in plain language.
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Heart pill puzzle: two at once or one by one?
Disease control CompletedThis study aimed to find the safest way for doctors to start two proven heart failure medications. It compared starting both drugs at the same time versus starting one first and adding the second later. The goal was to see if the simultaneous approach caused more side effects, li…
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION
Phase: PHASE4 • Sponsor: Universidade do Porto • Aim: Disease control
Last updated Apr 01, 2026 14:42 UTC
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Electronic nudges aim to keep heart failure patients on track after clinic
Disease control CompletedThis small pilot study tested whether electronic alerts in patient records could help pharmacists follow up with heart failure patients who might be missing their medications. The goal was to see if these reminders could improve long-term medication adherence after patients compl…
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION
Phase: NA • Sponsor: Northwestern University • Aim: Disease control
Last updated Mar 31, 2026 12:11 UTC
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Could a Two-Week ketone boost help a failing heart?
Disease control CompletedThis small study tested whether a two-week ketone supplement could improve how the heart uses energy in people with chronic heart failure. Twelve participants took the supplement and then a placebo, while researchers used advanced scans to measure changes in the heart's fuel cons…
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION
Phase: NA • Sponsor: Aarhus University Hospital • Aim: Disease control
Last updated Mar 31, 2026 12:11 UTC
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Can a heart pill prevent future hospitalizations after a heart attack?
Disease control CompletedThis study looked at whether a medication called vericiguat helps people who recently had a heart attack and have weakened heart pumping. Researchers followed 149 patients to see if those taking the drug regularly had fewer hospitalizations for heart failure or deaths from heart …
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION
Sponsor: The First Affiliated Hospital with Nanjing Medical University • Aim: Disease control
Last updated Mar 30, 2026 14:34 UTC
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New implant offers hope for failing hearts
Disease control CompletedThis small pilot study tested a new implanted device designed to help people with chronic heart failure. The device gently stimulates the diaphragm muscle in sync with the heartbeat, aiming to improve how the heart fills and pumps blood. Researchers compared 35 patients who recei…
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION
Phase: NA • Sponsor: VisCardia Inc. • Aim: Disease control
Last updated Mar 30, 2026 14:33 UTC
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New vs. old: which heart procedure works better for High-Risk patients?
Disease control CompletedThis study compared two different heart ablation techniques for people who have both atrial fibrillation (an irregular heartbeat) and heart failure. Researchers looked back at medical records from 700 patients to see if a newer technique called pulsed-field ablation works as well…
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION
Sponsor: St. Josefs-Hospital Wiesbaden GmbH • Aim: Disease control
Last updated Mar 30, 2026 14:31 UTC
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One pill, four drugs: a simpler way to manage heart failure?
Disease control CompletedThis study tested if combining four common heart failure medications into a single daily capsule helps patients take their medicine more consistently. Researchers worked with 35 adults who have a specific type of heart failure, including some who also have HIV, to see if this 'po…
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION
Phase: PHASE2 • Sponsor: University of California, San Francisco • Aim: Disease control
Last updated Mar 30, 2026 14:29 UTC
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New pill tested to help weakened hearts pump stronger
Disease control CompletedThis early-stage study tested a new oral medication called AC01 in people with chronic heart failure where the heart pumps weakly. The main goals were to check if the drug was safe and to see how the body processes it. Researchers also looked for early signs that the drug might i…
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION
Phase: PHASE1, PHASE2 • Sponsor: AnaCardio AB • Aim: Disease control
Last updated Mar 27, 2026 12:38 UTC
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Heart failure care breakthrough: system helps doctors prescribe Life-Saving drugs
Disease control CompletedThis study tested different support systems to help doctors better prescribe proven heart failure medications. Over 4,300 patients with weakened heart function participated across multiple clinics. Researchers compared usual care against computer alerts and pharmacist support to …
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION
Phase: NA • Sponsor: Geisinger Clinic • Aim: Disease control
Last updated Mar 25, 2026 14:08 UTC
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New heart failure pill tested in major trial
Disease control CompletedThis study tested whether a new drug called tovinontrine could help control chronic heart failure. It involved 557 adults with a weakened heart pump who were already on standard treatments. Researchers compared the drug to a placebo over 12 weeks, looking at changes in key blood …
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION
Phase: PHASE2 • Sponsor: Cardurion Pharmaceuticals, Inc. • Aim: Disease control
Last updated Mar 25, 2026 14:08 UTC
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Heart pump patients get boost from diabetes drug in new trial
Disease control CompletedThis study looked at whether a type of diabetes medication could help people with severe heart failure who have a mechanical heart pump (LVAD). Researchers wanted to see if the drug could reduce fluid buildup and strain on the heart, potentially leading to fewer hospital readmiss…
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION
Phase: PHASE4 • Sponsor: University of Chicago • Aim: Disease control
Last updated Mar 23, 2026 15:14 UTC
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Massive study reveals who gets key heart failure drugs
Knowledge-focused CompletedThis study looked back at the medical records of over 13,600 heart failure patients in France from 2021 to 2024. It tracked how often doctors prescribed a specific type of medication called SGLT2 inhibitors. The goal was to understand prescription trends and what factors influenc…
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION
Sponsor: Satelia • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:34 UTC