Smart app aims to optimize heart failure meds
NCT ID NCT05858320
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This completed Phase 3 trial tested a web application called SmartHF in 225 adults with heart failure and reduced ejection fraction. The app analyzes patient data and gives personalized medication recommendations that patients can share with their doctor. The goal was to see if using the app improves medication scores over 12 weeks compared to usual care.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
SmartHF web application (adaptive medication recommendations)
What this could lead to
If successful, this could provide a simple, patient-friendly tool to help doctors and patients optimize heart failure medications, potentially improving outcomes.
What could go wrong
This is a completed trial with 225 participants, so results are available but may not apply to all heart failure patients. The app only recommends medications; it does not prescribe them, so real-world impact depends on doctor uptake.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Emory University, Grady Hospital
Atlanta, Georgia, 30303, United States
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Henry Ford Hospital and Health System
Detroit, Michigan, 48202, United States
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Trinity Healthcare St. Joseph Mercy Ann Arbor
Ypsilanti, Michigan, 48197, United States
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University of Michigan
Ann Arbor, Michigan, 48109, United States
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Washington University, Barns Jewish Hospital
St Louis, Missouri, 63110, United States