Heart failure Drug's hidden effects revealed in new study
NCT ID NCT04498780
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at how the drug Sacubitril-Valsartan changes heart function in people with heart failure and reduced pumping ability. Researchers used a non-invasive method to measure heart pressure and volume in 117 participants. The goal is to uncover the mechanisms behind the drug's known benefits, such as fewer hospitalizations and better quality of life.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Sacubitril-Valsartan
What this could lead to
If successful, this could help doctors understand why Sacubitril-Valsartan improves symptoms and survival in heart failure patients.
What could go wrong
This is an observational study, not a treatment trial, so it won't directly test new therapies. Results may not change current practice.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Kardiopraxis Schirmer
Kaiserslautern, Germany
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University of Leipzig
Leipzig, Saxony, 04103, Germany