Could a diabetes drug ease heart failure in rare amyloid disease?

NCT ID NCT05795400

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested the drug dapagliflozin (a diabetes medicine) in 50 adults with heart failure due to amyloid cardiomyopathy, a rare condition where abnormal proteins stiffen the heart. Researchers measured changes in quality of life, walking distance, and heart stress markers over time. The goal was to see if the drug can safely ease symptoms and improve daily function.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • National Medical Research Center for Cardiology, Ministry of Health of Russian Federation

    Moscow, 121552, Russia

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