HEART FAILURE WITH PRESERVED EJECTION FRACTION
Clinical trials for HEART FAILURE WITH PRESERVED EJECTION FRACTION explained in plain language.
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New shot aims to cut heart failure deaths in obese patients
Disease control Recruiting nowThis study tests a new medicine called NNC0487-0111 in about 5,600 people who have both heart failure and obesity. Participants receive either the drug or a placebo as a weekly injection. The goal is to see if the drug reduces the risk of heart failure worsening, hospitalization,…
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION
Phase: PHASE3 • Sponsor: Novo Nordisk A/S • Aim: Disease control
Last updated Jul 01, 2026 22:00 UTC
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Can exercise and rehab keep older heart failure patients out of the hospital?
Disease control Recruiting nowThis trial tests whether a structured physical rehabilitation and exercise program can help older adults (age 60+) who have been hospitalized for heart failure with preserved ejection fraction (HFpEF). Participants will receive a progressive, multi-domain rehab intervention after…
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION
Phase: NA • Sponsor: Wake Forest University Health Sciences • Aim: Disease control
Last updated Jul 01, 2026 00:00 UTC
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Could a diabetes drug help heart failure patients after valve surgery?
Disease control Recruiting nowThis study tests whether a drug called enavogliflozin can prevent major heart problems or worsening heart failure in people who have had a heart valve replacement (TAVR) and still have heart failure. About 1,040 participants will receive either the drug or a placebo, in addition …
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION
Phase: PHASE4 • Sponsor: Duk-Woo Park, MD • Aim: Disease control
Last updated Jul 01, 2026 00:00 UTC
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Heart device trial aims to boost function in patients with preserved pumping ability
Disease control Recruiting nowThis study tests a small implanted device that sends gentle electrical signals to strengthen heart contractions in people with heart failure whose hearts still pump fairly well (ejection fraction 40-70%). Researchers will compare the device to a sham (inactive) implant in 1,500 p…
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION
Phase: NA • Sponsor: Impulse Dynamics • Aim: Disease control
Last updated Jun 28, 2026 00:00 UTC
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Could a Low-Calorie diet ease heart failure symptoms?
Disease control Recruiting nowThis study tests whether a 12-week low-calorie meal replacement diet can improve heart function and exercise ability in people with heart failure with preserved ejection fraction (HFpEF) who are also obese. 63 adults will be randomly assigned to either the diet or standard care. …
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION
Phase: PHASE2, PHASE3 • Sponsor: University of Leicester • Aim: Disease control
Last updated Jun 27, 2026 14:02 UTC
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New drug combo aims to ease heart failure symptoms and prevent hospital stays
Disease control Recruiting nowThis study tests whether adding vicadrostat to the standard medicine empagliflozin helps people with heart failure who have a preserved ejection fraction (heart pumps normally but is stiff). About 6000 adults with symptoms will take either vicadrostat plus empagliflozin or a plac…
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION
Phase: PHASE3 • Sponsor: Boehringer Ingelheim • Aim: Disease control
Last updated Jun 27, 2026 14:00 UTC
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Can a simple supplement combo help heart failure patients exercise longer?
Disease control Recruiting nowThis study is testing whether potassium nitrate, alone or combined with two supplements (propionyl-L-carnitine and nicotinamide riboside), can improve exercise endurance in people with a type of heart failure called HFpEF. About 53 participants will take these agents and undergo …
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION
Phase: PHASE2 • Sponsor: University of Pennsylvania • Aim: Disease control
Last updated Jun 27, 2026 13:02 UTC
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Could a new drug cut heart failure hospitalizations in people with obesity?
Disease control Recruiting nowThis phase 3 trial tests whether maridebart cafraglutide (MariTide) can reduce heart failure events like hospitalizations and urgent visits in people with obesity and a specific type of heart failure (preserved or mildly reduced ejection fraction). About 5,056 participants will r…
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION
Phase: PHASE3 • Sponsor: Amgen • Aim: Disease control
Last updated Jun 27, 2026 12:36 UTC
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New hope for stiff heart? drug trial targets common heart failure
Disease control Recruiting nowThis study tests an experimental drug (BMS-986435/MYK-224) in people with a specific type of heart failure where the heart pumps normally but is too stiff (HFpEF). The main goal is to check the drug's safety and how the body processes it. About 208 adults with stable symptoms wil…
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION
Phase: PHASE2 • Sponsor: Bristol-Myers Squibb • Aim: Disease control
Last updated Jun 27, 2026 12:31 UTC
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Could a smart pacemaker ease a common type of heart failure?
Disease control Recruiting nowThis study tests a modified pacemaker designed to improve heart function and quality of life in people with heart failure with preserved ejection fraction (HFpEF). About 105 participants will receive either the active pacing therapy or a non-pacing mode. Researchers will measure …
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION
Phase: NA • Sponsor: Medtronic Cardiac Rhythm and Heart Failure • Aim: Disease control
Last updated Jun 27, 2026 12:25 UTC
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New drug aims to ease lung pressure in heart failure patients
Disease control Recruiting nowThis study tests an experimental drug called TX000045 in 180 adults with pulmonary hypertension (high blood pressure in the lungs) caused by a type of heart failure where the heart pumps normally but doesn't relax properly. Participants will receive either the drug or a placebo f…
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION
Phase: PHASE2 • Sponsor: Tectonic Therapeutic • Aim: Disease control
Last updated Jun 27, 2026 12:01 UTC
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New drug aims to repair heart in common form of heart failure
Disease control Recruiting nowThis study tests a new medicine called CDR132L in 200 people with a type of heart failure where the heart is stiff and thickened. The goal is to see if it can improve heart structure and function. Participants will receive either the study drug or a placebo by chance, and the stu…
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION
Phase: PHASE2 • Sponsor: Novo Nordisk A/S • Aim: Disease control
Last updated Jun 27, 2026 11:00 UTC
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Can a diabetes drug duo protect your heart?
Disease control Recruiting nowThis study looks at whether combining two common diabetes drugs (GLP-1 agonists and SGLT2 inhibitors) can improve heart function and artery health in people with type 2 diabetes who are at high risk for heart problems. About 240 adults will be split into four groups, each receivi…
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION
Sponsor: University of Athens • Aim: Disease control
Last updated Jun 27, 2026 11:00 UTC
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New clinic aims to keep heart failure patients out of the hospital
Disease control Recruiting nowThis study tests a multidisciplinary clinic that provides heart failure patients with educational videos, a self-management kit, and follow-up phone calls after hospital discharge. The goal is to reduce 30-day readmission rates and improve patient satisfaction. The trial enrolls …
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION
Phase: NA • Sponsor: Hackensack Meridian Health • Aim: Disease control
Last updated Jun 27, 2026 09:04 UTC
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New electric pulse procedure could tame AFib in heart failure patients
Disease control Recruiting nowThis pilot study is testing a new procedure called electroporation ablation (using the FARAPULSE system) to treat atrial fibrillation in 200 people who also have heart failure with preserved ejection fraction. Half will get the procedure, half will get standard medical care. The …
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION
Phase: NA • Sponsor: Cardioangiologisches Centrum Bethanien • Aim: Disease control
Last updated Jun 27, 2026 09:02 UTC
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New pill aims to tackle heart failure and obesity together
Disease control Recruiting nowThis study tests an experimental drug called HRS-7535 in 225 adults who have both heart failure (with mildly reduced or preserved pumping ability) and obesity. Participants will receive either the drug or a placebo for 36 weeks to see if it helps with weight loss and reduces infl…
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION
Phase: PHASE2 • Sponsor: Shandong Suncadia Medicine Co., Ltd. • Aim: Disease control
Last updated Jun 27, 2026 08:07 UTC
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New program aims to get frail veterans into cardiac rehab
Disease control Recruiting nowThis study tests a program called Transition to Cardiac Rehabilitation (T2CR) for Veterans with heart disease who also have other health problems or frailty. The program starts in the hospital and continues at home, helping patients build skills and motivation to do cardiac rehab…
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION
Phase: NA • Sponsor: VA Office of Research and Development • Aim: Disease control
Last updated Jun 27, 2026 07:55 UTC
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New clinic aims to tackle obesity and heart disease together
Disease control Recruiting nowThis study tests whether a cardiometabolic clinic can help obese adults with heart disease lose weight and improve health. Sixty participants will receive care from the clinic and be followed for 12 months. Researchers will measure weight loss, body mass index, and fat distributi…
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION
Sponsor: Mayo Clinic • Aim: Disease control
Last updated Jun 27, 2026 07:55 UTC
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Could a pacemaker plus ablation beat pills for heart failure patients with AFib?
Disease control Recruiting nowThis study compares two approaches for people with permanent atrial fibrillation and heart failure with preserved ejection fraction. One group gets a pacemaker plus a procedure to ablate (destroy) the heart's AV node, while the other group continues with standard heart rate medic…
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION
Phase: NA • Sponsor: French Cardiology Society • Aim: Disease control
Last updated Jun 27, 2026 07:51 UTC
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Exercise MRI could spot hidden heart failure in breathless patients
Diagnosis Recruiting nowThis study aims to see if a special MRI done during exercise can help doctors better diagnose and predict outcomes in people with a type of heart failure called HFpEF. Researchers will enroll 400 adults, including those with HFpEF, those with shortness of breath from other causes…
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION
Sponsor: Mayo Clinic • Aim: Diagnosis
Last updated Jun 27, 2026 12:10 UTC
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Could a simple iron shot boost energy in heart failure?
Symptom relief Recruiting nowThis study looks at whether giving intravenous iron (Ferinject) to heart failure patients with low iron can improve their quality of life and walking ability. About 100 hospitalized adults with a specific type of heart failure (HFpEF) will receive either iron infusions plus diet …
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION
Phase: PHASE4 • Sponsor: Tomsk National Research Medical Center of the Russian Academy of Sciences • Aim: Symptom relief
Last updated Jun 27, 2026 14:02 UTC
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New group exercise study aims to help heart failure patients move better and feel better
Symptom relief Recruiting nowThis study is testing a new group exercise program combined with remote activity monitoring for older adults with heart failure with preserved ejection fraction (HFpEF). The goal is to see if this approach can improve exercise habits, physical function, and quality of life. About…
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION
Phase: NA • Sponsor: Wake Forest University Health Sciences • Aim: Symptom relief
Last updated Jun 27, 2026 12:37 UTC
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New pill HRS-1893 tested for stiff heart condition
Symptom relief Recruiting nowThis study tests a new drug called HRS-1893 in 48 adults with heart failure where the heart pumps normally but is too stiff (heart failure with preserved ejection fraction). The main goal is to check safety and side effects, while also looking at changes in heart stress markers a…
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION
Phase: PHASE2 • Sponsor: Shandong Suncadia Medicine Co., Ltd. • Aim: Symptom relief
Last updated Jun 27, 2026 12:32 UTC
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Could a simple pacemaker tweak ease heart failure?
Symptom relief Recruiting nowThis study tests whether adjusting a pacemaker's lower heart rate to an individual's optimal level can improve symptoms and quality of life in people with heart failure and bradycardia. Researchers will compare this personalized approach to the standard fixed rate of 60 beats per…
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION
Phase: NA • Sponsor: Samsung Medical Center • Aim: Symptom relief
Last updated Jun 27, 2026 12:28 UTC
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Can a simple supplement boost heart failure patients' strength?
Symptom relief Recruiting nowThis study looks at whether giving L-Citrulline, tetrahydrobiopterin (BH4), and atorvastatin can improve blood vessel function and physical ability in veterans with a type of heart failure called HFpEF. About 90 participants will take these medications and be tested on how well t…
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION
Phase: PHASE1 • Sponsor: VA Office of Research and Development • Aim: Symptom relief
Last updated Jun 27, 2026 12:23 UTC
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Can a diabetes drug and a salt compound boost exercise in heart failure?
Symptom relief Recruiting nowThis study tests whether empagliflozin (a diabetes drug) and potassium nitrate (a supplement) can improve exercise endurance in people with heart failure with preserved ejection fraction (HFpEF). About 53 participants will take one of three combinations of these drugs for a perio…
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION
Phase: PHASE2 • Sponsor: University of Pennsylvania • Aim: Symptom relief
Last updated Jun 27, 2026 12:07 UTC
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Could a common gout drug help heart failure patients breathe easier?
Symptom relief Recruiting nowThis study tests whether a low dose of colchicine, an anti-inflammatory drug, can improve exercise capacity in people with heart failure and chronic inflammation. Sixty participants will be randomly assigned to receive either colchicine or a placebo for three months. Researchers …
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION
Phase: PHASE2 • Sponsor: University of Texas Southwestern Medical Center • Aim: Symptom relief
Last updated Jun 27, 2026 09:08 UTC
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Iron shot boosts heart Patients' stamina, study hopes
Symptom relief Recruiting nowThis study tests whether a single dose of intravenous iron (ferric derisomaltose) can improve exercise capacity in people with heart failure with preserved ejection fraction who also have iron deficiency. About 66 adults will receive either the iron infusion or a placebo, and the…
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION
Phase: PHASE4 • Sponsor: Massachusetts General Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 09:06 UTC
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Pacemaker study aims to boost stamina in stubborn heart failure
Symptom relief Recruiting nowThis study looks at whether a pacemaker can improve exercise ability and quality of life in people with heart failure with preserved ejection fraction (HFpEF) who also have a small heart chamber and a low heart rate during activity. About 30 participants will get a pacemaker and …
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION
Phase: NA • Sponsor: Fundación para la Investigación del Hospital Clínico de Valencia • Aim: Symptom relief
Last updated Jun 27, 2026 08:03 UTC
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New heart failure drug gets first human safety test
Symptom relief Recruiting nowThis early-stage trial is testing a new drug called NNC0537-1482 in 36 adults with heart failure. The main goal is to check if the drug is safe and how the body handles it. Participants will receive either the drug or a placebo by injection, and neither they nor the doctors will …
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION
Phase: PHASE1 • Sponsor: Novo Nordisk A/S • Aim: Symptom relief
Last updated Jun 27, 2026 08:02 UTC
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Leg heat therapy shows promise for heart failure patients
Symptom relief Recruiting nowThis study tests whether daily leg heat therapy can help people with heart failure with preserved ejection fraction (HFpEF) exercise longer and feel better. Participants wear water-circulating trousers heated to 42°C for 90 minutes each day at home. The goal is to see if this imp…
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION
Phase: NA • Sponsor: Indiana University • Aim: Symptom relief
Last updated Jun 27, 2026 07:57 UTC
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Breathing workouts may boost exercise in heart failure patients
Symptom relief Recruiting nowThis study tests whether a special breathing exercise program, called inspiratory muscle training, can improve how well the breathing muscles work during exercise in people with heart failure. Researchers will measure blood flow to breathing and leg muscles, and how long particip…
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION
Phase: NA • Sponsor: Mayo Clinic • Aim: Symptom relief
Last updated Jun 27, 2026 07:55 UTC
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App-Based rehab could help heart failure patients get active at home
Symptom relief Recruiting nowThis study tests a home-based cardiac rehabilitation program delivered through a custom mobile app for people with heart failure. Participants use the app for education, mindfulness, and physical activity guidance, plus periodic video calls with an exercise physiologist. The goal…
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION
Phase: NA • Sponsor: Vanderbilt University Medical Center • Aim: Symptom relief
Last updated Jun 27, 2026 07:51 UTC
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Can muscle ultrasound predict heart failure recovery in seniors?
Knowledge-focused Recruiting nowThis study looks at 110 patients aged 80 and older who are in the hospital for acute heart failure. Researchers will use ultrasound and blood tests to measure muscle loss (sarcopenia) and see how it affects their recovery over six months. The goal is to find better ways to predic…
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION
Sponsor: Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:03 UTC
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Can Omega-3s cool inflammation in stiff hearts?
Knowledge-focused Recruiting nowThis early-phase study is testing whether omega-3 fatty acids can reduce inflammation in the heart muscle of people with heart failure with preserved ejection fraction (HFpEF). Researchers will use special MRI scans before and after an iron-based infusion to detect changes in inf…
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION
Phase: EARLY_PHASE1 • Sponsor: University of Florida • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:04 UTC
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Breathing Helium-Oxygen may unlock exercise secrets for heart failure patients
Knowledge-focused Recruiting nowThis study looks at whether breathing a low-density helium-oxygen gas mixture can reduce breathlessness and improve exercise capacity in people with heart failure with preserved ejection fraction (HFpEF) and obesity. Researchers will measure how much oxygen the body uses during b…
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION
Phase: NA • Sponsor: University of Texas Southwestern Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:30 UTC
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Heart MRI with manganese dye could reveal hidden clues in common heart failure
Knowledge-focused Recruiting nowThis study uses advanced MRI scans with a special manganese dye to look at how the heart handles calcium and energy in people with heart failure with preserved ejection fraction (HFpEF). Researchers will compare 40 people with HFpEF (half with type 2 diabetes) and 20 healthy volu…
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION
Sponsor: University of Leicester • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:26 UTC
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New scan could reveal hidden heart inflammation in common heart failure
Knowledge-focused Recruiting nowThis study is testing a special PET scan that uses a tracer called 68Ga-FAPI to look for inflammation and scarring in the hearts of people with a specific type of heart failure (HFpEF). About 35 adults with this condition will get the scan to see how well it works. The goal is to…
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION
Phase: PHASE2 • Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:24 UTC
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Kidney Drug's hidden heart benefits under the microscope
Knowledge-focused Recruiting nowThis study looks at how dapagliflozin, a diabetes drug, affects heart function and metabolism in people with chronic kidney disease. Researchers will measure heart strain, oxygen use during exercise, and blood chemicals in 60 adults. The goal is to understand how the drug works b…
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION
Phase: PHASE1, PHASE2 • Sponsor: Northwestern University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:06 UTC
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HeartShare study aims to crack the code of heart failure
Knowledge-focused Recruiting nowThis study is looking at 1,000 people with and without heart failure to better understand the different types of the condition. Researchers will use heart images and blood tests to find patterns that could lead to more personalized treatments. The goal is to improve care for peop…
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION
Sponsor: Northwestern University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:06 UTC
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Heart biopsy study aims to unlock secrets of heart failure
Knowledge-focused Recruiting nowThis study looks at heart tissue from 180 people with a type of heart failure called HFpEF. Researchers take tiny samples of heart muscle during a routine procedure to find changes in the tissue. The goal is to learn what causes this condition so better treatments can be develope…
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION
Sponsor: Northwestern University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:05 UTC
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Diabetes Drug's hidden power: could it boost heart and muscle energy?
Knowledge-focused Recruiting nowThis study looks at how a common diabetes drug (SGLT2 inhibitor) changes the way the heart and muscles use energy from ketones. Researchers want to see if these changes can improve exercise ability and daily function in 30 adults with type 2 diabetes and heart failure. Participan…
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION
Phase: EARLY_PHASE1 • Sponsor: The University of Texas Health Science Center at San Antonio • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:04 UTC
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Blood cells may reveal hidden heart risks in diabetes patients
Knowledge-focused Recruiting nowThis study aims to find early warning signs of heart failure in people with type 2 diabetes and metabolic syndrome by analyzing immune cells from a blood sample. Researchers will compare calcium and inflammation signals in these cells between patients with and without heart probl…
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION
Sponsor: Hospices Civils de Lyon • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:01 UTC
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Tiny study hopes exercise can boost heart health in stubborn heart failure
Knowledge-focused Recruiting nowThis pilot study is testing whether a 12-week monitored exercise program can improve heart health in veterans with a type of heart failure called HFpEF. Only 4 participants are being enrolled to see if the facility can support a larger study and if exercise shows any benefit with…
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION
Sponsor: Columbia VA Health Care System • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC
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Heart tissue study seeks clues to postmenopausal heart failure
Knowledge-focused Recruiting nowThis study looks at why postmenopausal women have a higher risk of diastolic heart failure. Researchers will examine heart tissue from 500 patients undergoing cardiac surgery to study how estrogen loss affects heart energy and blood vessel health. The goal is to better understand…
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION
Sponsor: Beth Israel Deaconess Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:03 UTC
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New heart MRI techniques could revolutionize stress testing
Knowledge-focused Recruiting nowThis study is testing new heart MRI techniques to see how the heart adapts to stress, like exercise or fluid changes. Researchers will study 135 healthy volunteers and people with heart conditions. The goal is to improve understanding of heart function and develop better diagnost…
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION
Phase: NA • Sponsor: Sheffield Teaching Hospitals NHS Foundation Trust • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:02 UTC
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Yale launches massive heart failure registry to monitor Real-World care
Knowledge-focused Recruiting nowThis study creates a live registry of up to 40,000 heart failure patients across the Yale New Haven Health System. Researchers will track hospitalizations and use of recommended therapies like beta blockers and ACE inhibitors. The goal is to monitor and improve heart failure care…
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION
Sponsor: Yale University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:11 UTC
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Tiny heart device tested in MRI study for common type of heart failure
Knowledge-focused Recruiting nowThis study uses a special heart MRI to see if a device called a coronary sinus reducer can improve blood flow in patients with heart failure with preserved ejection fraction (HFpEF) and coronary microvascular dysfunction (small vessel disease). The device is implanted to reroute …
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION
Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:08 UTC
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Could ditching Beta-Blockers improve heart function?
Knowledge-focused Recruiting nowThis study looks at what happens when people with a certain type of heart failure (HFpEF) stop taking beta-blockers for 4 weeks. Researchers will measure changes in heart function, exercise ability, and quality of life in 30 participants. The goal is to see if stopping this commo…
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION
Phase: NA • Sponsor: UConn Health • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:52 UTC