New drug aims to repair heart in common form of heart failure
NCT ID NCT06979362
First seen Jun 27, 2026 · Last updated Jul 10, 2026 · Updated 2 times
Summary
This study tests a new medicine called CDR132L in 200 people with a type of heart failure where the heart is stiff and thickened. The goal is to see if it can improve heart structure and function. Participants will receive either the study drug or a placebo by chance, and the study lasts about 60 weeks.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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1 Wojskowy Szpital Kliniczny z Poliklinika SPZOZ
NOT_YET_RECRUITINGLublin, Lublin Voivodeship, 20-049, Poland
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4 Wojskowy Szpital Kliniczny Z Poliklinika Samodzielny Publiczny Zaklad Opieki Zdrowotnej We Wroclawiu
RECRUITINGWroclaw, Lower Silesian Voivodeship, 50-981, Poland
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Abington Memorial Hospital
COMPLETEDAbington, Pennsylvania, 19001, United States
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AdventHealth Orlando
NOT_YET_RECRUITINGOrlando, Florida, 32803, United States
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All India Institute of Medical Sciences (AIIMS), Nagpur
RECRUITINGNagpur, Maharashtra, 441108, India
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All India Institute of Medical Sciences (AIIMS), Nagpur
NOT_YET_RECRUITINGNagpur, Maharashtra, 441108, India
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Amarillo Medical Specialists
NOT_YET_RECRUITINGAmarillo, Texas, 79124, United States
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American Heart of Poland S.A.
RECRUITINGBielsko-Biala, 43-316, Poland
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Apollo Hospital Chennai
RECRUITINGChennai, Tamil Nadu, 600006, India
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Apollo Hospital Chennai
NOT_YET_RECRUITINGChennai, Tamil Nadu, 600006, India
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Capital Area Research LLC
RECRUITINGCamp Hill, Pennsylvania, 17011, United States
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Cardio Health Clinical Trials
NOT_YET_RECRUITINGHamilton, Ontario, L8W 3K5, Canada
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Cardio Health Clinical Trials
RECRUITINGMississauga, Ontario, L5M 2S6, Canada
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Charité - Campus Benjamin Franklin - Klinik für Kardiologie
NOT_YET_RECRUITINGBerlin, 12203, Germany
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Charité - Campus Virchow-Klinikum - Kardiologie, Angiologie und Intensivmedizin (CRU)
RECRUITINGBerlin, 13353, Germany
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Chungbuk National University Hospital
RECRUITINGCheongju-si, 28644, South Korea
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Duke University
RECRUITINGDurham, North Carolina, 27710, United States
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East Texas Cardiology PA
RECRUITINGHouston, Texas, 77002, United States
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G B Pant Institute of Postgraduate Medical Education and Research
RECRUITINGNew Delhi, National Capital Territory of Delhi, 110022, India
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Government Siddhartha Medical College & Government General Hospital, Vijayawada
RECRUITINGVijayawada, NTR District, Andhra Pradesh, 520008, India
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Guardian Research Org LLC
NOT_YET_RECRUITINGWinter Park, Florida, 32792, United States
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Hamilton General Hospital
COMPLETEDHamilton, Ontario, L8L 5G4, Canada
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Hamilton Hlth Sc. - General Site
NOT_YET_RECRUITINGHamilton, Ontario, L8L 2X2, Canada
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Harbor-UCLA Medical Center
RECRUITINGTorrance, California, 90502, United States
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Henry Ford Hospital_Detroit
RECRUITINGDetroit, Michigan, 48202, United States
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Hosp. U Gran Canaria Dr. Negrín_Cardiologia
NOT_YET_RECRUITINGLas Palmas de Gran Canaria, 35010, Spain
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Hospital Clinico Universitario de Valencia
RECRUITINGValencia, 46010, Spain
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Hospital Ramón y Cajal_Cardiología
NOT_YET_RECRUITINGMadrid, 28034, Spain
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Hospital Univ. Virgen de la Arrixaca
RECRUITINGEl Palmar, Murcia, 30120, Spain
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Hospital Universitario La Paz
RECRUITINGMadrid, 28046, Spain
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Hospital Universitario San Cecilio
RECRUITINGGranada, Andalusia, 18016, Spain
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Hospital del Mar
RECRUITINGBarcelona, 08003, Spain
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Hyogo Prefectural HarimaHimeji General Medical Center_Cardiology
RECRUITINGHimeji-shi, Hyogo, 670-8560, Japan
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IPGME&R and SSKM Hospital
RECRUITINGKolkata, West Bengal, 700020, India
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IUCPQ - Universite Laval
NOT_YET_RECRUITINGQuébec, G1V 4G5, Canada
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Icahn Sch of Med-Mt Sinai Hosp
NOT_YET_RECRUITINGNew York, New York, 10029, United States
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Inova Heart and Vascular Institute
RECRUITINGFalls Church, Virginia, 22042, United States
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Inpatient Research Clinic LLC
RECRUITINGMiami Lakes, Florida, 33014, United States
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Instytut Centrum Zdrowia Matki Polki
RECRUITINGLodz, 93-338, Poland
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Kagawa University Hospital_Cardiology
COMPLETEDKita-gun, Kagawa, 761-0793, Japan
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Keimyung University Dongsan Hospital
RECRUITINGDaegu, 42601, South Korea
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King's College Hospital
RECRUITINGLondon, SE5 9RS, United Kingdom
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Kobe City Medical Center General Hospital_Cardiology
RECRUITINGKobe-shi, Hyogo, 650-0047, Japan
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Korea University Anam Hospital
RECRUITINGSeoul, 02841, South Korea
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Korea University Guro Hospital
COMPLETEDSeoul, 08308, South Korea
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Korea University Guro Hospital
WITHDRAWNSeoul, 08308, South Korea
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Krakowski Szpital Specjalistyczny im. Jana Pawla II
COMPLETEDKrakow, 31-202, Poland
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Medical Research Institute KITANO HOSPITAL_Cardiovascular Medicine
RECRUITINGOsaka-shi, Osaka, 530-8480, Japan
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Medizinische Hochschule Hannover - Kardiologie und Angiologie
RECRUITINGHanover, 30625, Germany
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Mitoyo General Hospital_Cardiovascular medicine
NOT_YET_RECRUITINGKagawa, 769-1695, Japan
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NIPPON MEDICAL SCHOOL HOSPITAL_Cardiovascular medicine
RECRUITINGBunkyo-ku, Tokyo, 113-8603, Japan
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Narodowy Instytut Kardiologii Stefana Kardynala Wyszynskiego Panstwowy Instytut Badawczy
COMPLETEDWarsaw, 04-628, Poland
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National Hospital Organization Mito Medical Center_Cardiovascular medicine
RECRUITINGIbaraki, 311-3193, Japan
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National Hospital Organization Yokohama Medical Center_Cardiology
RECRUITINGYokohama-shi, Kanagawa, 245-8575, Japan
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Ome medical center_Cardiology
NOT_YET_RECRUITINGOme-shi, Tokyo, 198-0042, Japan
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Osaka Metropolitan University Hospital_Cardiovascular Medicine
RECRUITINGOsaka-Shi, Osaka, 545-8586, Japan
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Osmania General Hospital
RECRUITINGHyderabad, Telangana, 500012, India
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Osmania General Hospital
NOT_YET_RECRUITINGHyderabad, Telangana, 500012, India
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Pima Heart and Vascular
NOT_YET_RECRUITINGTucson, Arizona, 85741, United States
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Pomorski Uniwersytet Medyczny
NOT_YET_RECRUITINGSzczecin, West Pomeranian Voivodeship, 71-252, Poland
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Premier Clinical Trial Research Network (PCTRN)
NOT_YET_RECRUITINGHamilton, Ontario, L8L 5G4, Canada
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Providence St. Vincent Heart
COMPLETEDPortland, Oregon, 97225, United States
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Rhythm Heart Institute - A unit of Synergy Lifecare Pvt
RECRUITINGVadodara, Gujarat, 390022, India
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Samodzielny Publiczny Zaklad Opieki Zdrowotnej Szpital Uniwersytecki w Krakowie
NOT_YET_RECRUITINGKrakow, 30-688, Poland
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Sana Kliniken Berlin-Brandenburg GmbH - Lichtenberg
COMPLETEDBerlin, 10365, Germany
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Sapporo Medical University Hospital_Cardiovascular, Kidney, Metabolism Endocrinology
RECRUITINGSapporo-shi, Hokkaido, 060-8543, Japan
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Sengupta Hospital and Research Institute
RECRUITINGNagpur, Maharashtra, 440033, India
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Sentara Bayside Hospital
COMPLETEDNorfolk, Virginia, 23507-1904, United States
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Seoul National University Bundang Hospital
COMPLETEDSeongnam-si, Gyeonggi-do, 13620, South Korea
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Shri Mahant Indiresh Hospital
RECRUITINGDehradun, Uttarakhand, 248001, India
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Sir Ganga Ram Hospital-Cardiology
RECRUITINGNew Delhi, 110060, India
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Slaskie Centrum Chorob Serca W Zabrzu
NOT_YET_RECRUITINGZabrze, 41-800, Poland
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Southampton General Hospital
RECRUITINGSouthampton, SO16 6YD, United Kingdom
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St Bartholomew's Hospital - Cardiac Research Office
NOT_YET_RECRUITINGLondon, EC1A 7BE, United Kingdom
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St Bartholomew's Hospital - Cardiology
RECRUITINGLondon, EC1A 7BE, United Kingdom
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St Pauls Hospital
COMPLETEDVancouver, British Columbia, V6Z1Y6, Canada
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St. Michael's Hospital
NOT_YET_RECRUITINGToronto, Ontario, M5B 1W8, Canada
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Szpital Specjalistyczny im. Ludwika Rydygiera w Krakowie Sp. z o.o.
RECRUITINGKrakow, 31-826, Poland
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TMC Hlthcr Clin Res Office
NOT_YET_RECRUITINGTucson, Arizona, 85712, United States
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Texama Medical Center
NOT_YET_RECRUITINGDenison, Texas, 75020, United States
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The James Cook University Hospital - Cardiology
RECRUITINGMiddlesbrough, TS4 3BW, United Kingdom
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The Royal Brompton Hospital - Respiratory CRF
RECRUITINGLondon, SW3 6HP, United Kingdom
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Trialmed - Midlands
RECRUITINGBirmingham, B16 8QQ, United Kingdom
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UCSD NAFLD Research Center
RECRUITINGLa Jolla, California, 92037, United States
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Uniklinik Schleswig-Holstein - Med. Klinik III Kardiologie und Internist. Intensivmedizin
RECRUITINGKiel, 24105, Germany
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Uniklinik TU Dresden - Herzzentrum Dresden GmbH
RECRUITINGDresden, 01307, Germany
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UniklinikHeidelberg - Innere Med. III - Kardiologie, Angiologie, Pneumologie
RECRUITINGHeidelberg, 69120, Germany
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Univ of Alabama Birmingham
RECRUITINGBirmingham, Alabama, 35233, United States
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Univ of Colorado at Denver
NOT_YET_RECRUITINGAurora, Colorado, 80045, United States
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Universitaetsklinikum Essen - Klinik für Kardiologie und Angiologie
NOT_YET_RECRUITINGEssen, 45147, Germany
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University of California San Francisco UCSF
RECRUITINGSan Francisco, California, 94143, United States
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University of California, San Francisco
RECRUITINGSan Francisco, California, 94110, United States
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University of Minnesota_Minneapolis_1
COMPLETEDMinneapolis, Minnesota, 55455, United States
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University of Ottawa Heart Institute (UOHI)
RECRUITINGOttawa, Ontario, K1Y 4W7, Canada
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University of Texas Southwestern Medical Center
RECRUITINGDallas, Texas, 75390-9302, United States
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Universitätsklinikum Frankfurt aM - Kardiologie
RECRUITINGFrankfurt am Main, 60596, Germany
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Universitätsklinikum Halle - Innere Medizin III
RECRUITINGHalle, 06120, Germany
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Uniwersytecki Szpital Kliniczny Im. Jana Mikulicza-Radeckiego We Wroclawiu
RECRUITINGWroclaw, 50-556, Poland
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Uniwersytecki Szpital Kliniczny Nr 4 W Lublinie
RECRUITINGLublin, 20-090, Poland
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Uniwersytecki Szpital Kliniczny w Bialymstoku
RECRUITINGBialystok, Podlaskie Voivodeship, 15-276, Poland
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UofL Health Care Outpatient
NOT_YET_RECRUITINGLouisville, Kentucky, 40202, United States
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VMMC & Safdarjung Hospital
RECRUITINGNew Dehli, New Delhi, 110029, India
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VMMC & Safdarjung Hospital
NOT_YET_RECRUITINGNew Dehli, New Delhi, 110029, India
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Valley Clinical Trials
RECRUITINGCovina, California, 91723, United States
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Valley Clinical Trials
RECRUITINGNorthridge, California, 91325, United States
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Vanderbilt University Medical Center
RECRUITINGNashville, Tennessee, 37232, United States
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Washington University School of Medicine
RECRUITINGSt Louis, Missouri, 63110, United States
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William Osler Hel Bra Civic Hs
NOT_YET_RECRUITINGBrampton, Ontario, L6R 3J7, Canada
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Winchester Dist Memorial Hosp
RECRUITINGWinchester, Ontario, K0C 2K0, Canada
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Wojewodzki Szpital Im. Sw.Ojca Pio W Przemyslu
RECRUITINGPrzemyśl, 37-700, Poland
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Women's College Hospital
NOT_YET_RECRUITINGToronto, Ontario, M5S 1B1, Canada
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Wonju Severance Christian Hospital
RECRUITINGGangwon-do, 26426, South Korea
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Wycombe General Hospital
RECRUITINGHigh Wycombe, HP11 2TT, United Kingdom
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Yokohama City University Medical Center_Cardiovascular Center
RECRUITINGKanagawa, 232-0024, Japan
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Yokohama City University Medical Center_Cardiovascular Center
NOT_YET_RECRUITINGKanagawa, 232-0024, Japan
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