Novo Nordisk A/s

This study looks at how a new investigational medicine called CagriSema affects the body's energy use compared to a calorie-reduced diet. About 80 adults with obesity will be randomly assigned to either CagriSema or a weight-loss diet for the first part, then everyone gets CagriS…

This study tests if a new insulin taken once a week (insulin icodec) controls blood sugar as well as a standard daily insulin (insulin glargine) in adults with type 1 diabetes. About 877 participants will use either weekly or daily insulin, plus rapid-acting insulin at meals, for…

This study tests a new medicine called CDR132L in 200 adults with heart failure and an enlarged heart. Participants will receive either the drug or a placebo for about 60 weeks to see if it improves heart structure and function. The goal is to find a new way to control heart fail…

This study tests a new medicine, NNC6019-0001, to see if it can lower the risk of heart-related death and hospital stays in people with transthyretin amyloid cardiomyopathy (ATTR-CM), a condition where abnormal proteins build up in the heart. About 1,280 adults with ATTR-CM will …

This study tests whether a new medicine called ziltivekimab can reduce plaque buildup in heart arteries after a heart attack. About 332 adults who recently had a heart attack will receive either the study drug or a placebo for around 15 months. The goal is to see if the drug help…

This study looks at how well oral semaglutide works for managing blood sugar and weight in adults with type 2 diabetes. About 470 participants will take the pill as prescribed by their doctor and be followed for about 6 months. Researchers will measure changes in blood sugar leve…

This study tests if a once-weekly insulin shot (icodec) works as well as daily insulin shots for controlling blood sugar in people with type 2 diabetes. About 586 adults who have never used insulin before will take either the weekly or a daily insulin for 13 months. The goal is t…

This early-stage study is testing a new medicine called NNC0487-0111 in 80 adults with type 2 diabetes. The goal is to see how it affects the body's use of insulin and how well the pancreas works. Participants are randomly assigned to receive either the study drug or a placebo. T…

This study looks at how well a new insulin called insulin icodec controls blood sugar in people with type 1 diabetes who have never used it before. About 245 participants will take the insulin as prescribed by their doctor for 22 to 30 weeks. Researchers will track changes in blo…

This study tests a new oral medicine called Inno8 in 30 adults with hemophilia A. The main goal is to see if different doses are safe. The study lasts about 11 weeks and is still recruiting.

This study tests a new medicine called NNC0487-0111, given as a weekly shot, to see if it helps people with obesity lose weight safely. About 1,150 adults will receive either the active drug or a placebo (dummy shot) for several months. The main goal is to measure how much body w…

This early-stage study tests an experimental drug called NNC4004-0002 in 60 adults with high uric acid but no symptoms. The main goal is to check if a single injection under the skin is safe and well-tolerated. Researchers will also measure how well it lowers uric acid levels. Pa…

This early-stage study looks at whether combining two experimental weight-loss drugs (cagrilintide and NNC0480-0389) causes less nausea, vomiting, and diarrhea than taking cagrilintide alone. About 100 women with overweight or obesity will receive both combinations at different t…

This early-stage study tests whether a once-weekly injection called NNC0487-0111 can lower how much people with obesity eat and how hungry they feel. About 120 adults aged 18-64 will receive either the drug or a placebo for up to 34 weeks. Researchers will measure changes in tota…

This study follows up with people who previously received the experimental obesity drug INV-347 in an earlier study. Participants will not receive any new treatment. The goal is to track any side effects and measure how long the drug stays in the body. About 91 adults aged 18 and…