New weekly shot aims to tame type 2 diabetes

NCT ID NCT07668388

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a new medicine called UBT251, given as a weekly shot, in 300 adults with type 2 diabetes. Some participants will get UBT251, others will get a placebo or an existing drug (semaglutide). The goal is to see if UBT251 can safely lower blood sugar and help with weight loss.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

UBT251 (a weekly injection for type 2 diabetes)

What this could lead to

If successful, UBT251 could offer a new once-weekly option to help control blood sugar and possibly reduce weight in people with type 2 diabetes.

What could go wrong

This is an early Phase 2 dose-finding study, so it is not yet proven effective or safe. Side effects are unknown, and results may not lead to a better treatment than existing options like semaglutide.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

type 2 diabetes mellitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • 1 Wojskowy Szpital Kliniczny z Poliklinika SPZOZ

    Lublin, Lublin Voivodeship, 20-049, Poland

  • ARETEUS s.r.o.

    Trebišov, 075 01, Slovakia

  • Ark Clinical Research

    Fountain Valley, California, 92708, United States

  • Ark Clinical Research

    Long Beach, California, 90815, United States

  • Asan Medical Center_Endocrinology

    Seoul, 05505, South Korea

  • Baker Heart and Diabetes Institute

    Melbourne, Victoria, 3004, Australia

  • CRS Clinical Research Mannheim GmbH (hVIVO Mannheim)

    Mannheim, 68167, Germany

  • Castle Hill Medical Centre

    Castle Hill, New South Wales, 2154, Australia

  • Catalina Research Institute, LLC

    Montclair, California, 91763, United States

  • Chosun University Hospital_Endocrinology

    Gwangju, 61453, South Korea

  • Chrysalis Clinical Research

    St. George, Utah, 84790, United States

  • Clinica Korall S.R.L. Satu Mare

    Satu Mare, 440055, Romania

  • Clinical Best Solutions Sp. z o.o., Sp. k

    Lublin, 20-011, Poland

  • Consano Clin Res-Shavano Park

    Shavano Park, Texas, 78231, United States

  • Cotton O'Neil Diabetes & Endocrinology

    Topeka, Kansas, 66606, United States

  • DSP Bochum, Diabetes- und Stoffwechselpraxis

    Bochum, 44869, Germany

  • Eap Osona Sud Alt Congost S.L.P

    Centelles (Barcelona), 08540, Spain

  • Encore Medical Research LLC

    Hollywood, Florida, 33021, United States

  • Encore Medical Research of Weston

    Weston, Florida, 33331, United States

  • Equip D'assistencia Primaria Vic S.L.P.

    Vic, Barcelona, 08500, Spain

  • Flourish Research

    Birmingham, Alabama, 35205, United States

  • Formed 2 Sp. z o.o.

    Oświęcim, 32-600, Poland

  • H. Infanta Luisa_Endocrino y Obesidad

    Seville, 41010, Spain

  • Herz- und Diabeteszentrum NRW - Bad Oeynhausen

    Bad Oeynhausen, 32545, Germany

  • Hospital Universitario Marqués de Valdecilla

    Santander, 39008, Spain

  • Hospital Universitario de la Princesa

    Madrid, 28006, Spain

  • Hospital Vall d'Hebron

    Barcelona, 08035, Spain

  • Hunter Medical Research Institute - Endocrinology and Diabetes

    New Lambton Heights, New South Wales, 2305, Australia

  • IMA Clinical Research

    Austin, Texas, 78745, United States

  • IN-DIA s.r.o.

    Lučenec, 984 01, Slovakia

  • InnoDiab Forschung GmbH

    Essen, 45136, Germany

  • KDCILM, LLC & Accellacare US, Inc.

    Wilmington, North Carolina, 28401, United States

  • Korea University Guro Hospital_Endocrinology

    Seoul, 08308, South Korea

  • LifeDoc Health

    Memphis, Tennessee, 38115, United States

  • Los Angeles Institute for Metabolic Research

    Los Angeles, California, 90015, United States

  • MD Medical Research

    Oxon Hill, Maryland, 20745, United States

  • MEDI-DIA s.r.o.

    Sabinov, 08301, Slovakia

  • MEDISPEKTRUM s.r.o.

    Bratislava, 851 01, Slovakia

  • Mariodiab Clinic SRL

    Brasov, 500101, Romania

  • Medizinisches Versorgungszentrum Am Bahnhof Spandau GbR

    Berlin, 13597, Germany

  • Mesut Durmaz, Hof

    Hof, 95030, Germany

  • Midwest Inst For Clin Res

    Indianapolis, Indiana, 46260, United States

  • Monroe Biomedical Research, LLC

    North Charleston, South Carolina, 29406, United States

  • NZOZ Vita-Diabetica Malgorzata Buraczyk

    Bialystok, Podlaskie Voivodeship, 15-879, Poland

  • PVN Kutató Kft.

    Budapest, 1102, Hungary

  • PharmQuest

    Greensboro, North Carolina, 27408, United States

  • Plains Clinical Research Center, LLC_Fargo

    Fargo, North Dakota, 58104, United States

  • Preferred Primary Care Physicians, Inc.

    Uniontown, Pennsylvania, 15401, United States

  • Private Practice - Dr. Laila A. Hassan

    Houston, Texas, 77089, United States

  • Pécsi Tudományegyetem ÁOK

    Pécs, 7624, Hungary

  • Quality Research Inc

    San Antonio, Texas, 78209, United States

  • Radiance Clinical Research

    Lampasas, Texas, 76550, United States

  • Roger Chih Yu Chen

    Sydney, New South Wales, 2148, Australia

  • Royal Adelaide Hospital - Cardiology Department

    Adelaide, South Australia, 5000, Australia

  • S.C Milena Sante SRL

    Galati, 800001, Romania

  • S.C. Top Diabet Srl

    Craiova, Dolj, 200515, Romania

  • SC Nutrilife SRL

    Bucharest, 013764, Romania

  • Semmelweis Egyetem

    Budapest, 1083, Hungary

  • South Broward Research LLC

    Miramar, Florida, 33027, United States

  • Specjalistyczna Praktyka Lekarska Diabetologia, Leczenie Cukrzycy i Otyłości lek. Monika Piwowar

    Kielce, 25-355, Poland

  • Spitalul Clinic Judetean De Urgenta Pius Brinzeu Timisoara

    Timișoara, 300723, Romania

  • Studiengesellschaft Dres. Könemann/Steinmann GbR

    Bünde, 32257, Germany

  • Szegedi Tudomanyegyetem St Györgyi Albert Klinikai Központ

    Szeged, Csongrád-Csanád, 6725, Hungary

  • Szent Margit Rendelőintézet Nonprofit Kft.

    Budapest, 1032, Hungary

  • Tekton Research Inc

    San Antonio, Texas, 78258, United States

  • The Catholic University of Korea, Seoul ST. Mary's Hospital_Endocrinology

    Seoul, 06591, South Korea

  • The Vancouver Clinic

    Vancouver, Washington, 98664, United States

  • Uniwersytecki Szpital Kliniczny w Bialymstoku

    Bialystok, 15-276, Poland

  • Versdias - Diabetologikum Amberg

    Amberg, Bavaria, 92224, Germany