New weekly injection could help fight obesity

NCT ID NCT07339423

Recruiting now Disease control Sponsor: Novo Nordisk A/S Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jul 10, 2026 · Updated 3 times

Summary

This study tests a new drug called NNC0487-0111, given as a once-weekly injection, to see if it helps people with obesity lose weight safely. About 1,150 adults who have tried to lose weight before will receive either the drug or a placebo. The main goal is to measure how much body weight they lose over time.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: NNC0487-0111 (a once-weekly injection for weight loss)
What this could lead to: If it works, this could offer a new once-weekly treatment option for obesity, helping people lose weight and improve health.
What could go wrong: This is a Phase 3 trial, but results are not yet known. The drug may not work better than placebo, and side effects are possible. It is not a cure for obesity.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

Obesity obesity disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

OBESITY

Contacts and locations

Show contact details

Study contacts

Contact

Email: •••••@•••••

Locations

AZ Delta - Roeselare
RECRUITING

Roeselare, 8800, Belgium
Accellacare and KDCILM, LLC
RECRUITING

Wilmington, North Carolina, 28401, United States
Albany House Medical Centre
RECRUITING

Wellingborough, NN8 4RW, United Kingdom
Amarillo Medical Specialists
RECRUITING

Amarillo, Texas, 79124, United States
C-Health Partners
RECRUITING

Calgary, Alberta, T2V 4J2, Canada
CENTRE DE RECHERCHE CLINIQUE PORTES DU SUD_Service d'Endocrinologie-Diabétologie-Maladies Métaboliques
RECRUITING

Vénissieux, 69200, France
CENTRE HOSPITALIER UNIVERSITAIRE DE TOULOUSE-HOPITAL RANGUEIL-Service de diabétologie et nutrition
RECRUITING

Toulouse, 31059, France
CHU NANTES - HOPITAL NORD LAENNEC_Service d'Endocrinologie-Diabétologie-Nutrition
RECRUITING

Saint-Herblain, 44800, France
CIPADI
RECRUITING

Godoy Cruz, M5501ARP, Argentina
Care United Research, LLC
RECRUITING

Forney, Texas, 75126, United States
Centro Medico Dra. Laura Maffei e Investigacion Clínica Apli
RECRUITING

Buenos Aires, C1425AGC, Argentina
Clifton Medical Centre
RECRUITING

Rotherham, S65 1DA, United Kingdom
Clinical Neuroscience Solution
RECRUITING

Orlando, Florida, 32801, United States
Clinical Res Collaborative
RECRUITING

Cumberland, Rhode Island, 02864, United States
Coastal Carolina Research Ctr
RECRUITING

North Charleston, South Carolina, 29405, United States
EMS Healthcare
RECRUITING

Cheshire, CH65 4LE, United Kingdom
Endeavor Health
RECRUITING

Skokie, Illinois, 60077, United States
Forschungszentrum Ruhr KliFoCenter GmbH, Kahrmann
RECRUITING

Witten, 58455, Germany
Fowey River Practice
RECRUITING

Fowey, Cornwall, PL23 1DT, United Kingdom
Fundación CESIM
RECRUITING

Santa Rosa, La Pampa Province, 6300, Argentina
G.A. Research Associates Ltd.
RECRUITING

Moncton, New Brunswick, E1G 1A7, Canada
Gentofte Hospital - Center for Klinisk Metabolisk Forskning
RECRUITING

Hellerup, 2900, Denmark
HCL-HOPITAL LYON SUD_Service d'Endocrinologie-Diabète-Nutrition
RECRUITING

Pierre-Bénite, 69310, France
HMC Health - Heston - The Meadows Centre for Health
RECRUITING

Hounslow, TW4 7NJ, United Kingdom
HOPITAL EUROPEEN GEORGES POMPIDOU_Service de nutrition et diabétologie
RECRUITING

Paris, 75015, France
HUB - Hôpital Erasme
RECRUITING

Brussels, 1070, Belgium
Health Res of Hampton Roads
RECRUITING

Newport News, Virginia, 23606, United States
Heart of Australia
RECRUITING

Chelmer, Queensland, 4068, Australia
Herz- und Diabeteszentrum NRW - Bad Oeynhausen
RECRUITING

Bad Oeynhausen, 32545, Germany
Hillcrest Clinical Research
RECRUITING

Simpsonville, South Carolina, 29681-1538, United States
Hillerød Endokrinologisk amb. H0652
RECRUITING

Hillerød, 3400, Denmark
Hope Clin Res & Wellness
RECRUITING

Conyers, Georgia, 30094, United States
Hunter Diabetes Centre
RECRUITING

Merewether, New South Wales, 2291, Australia
Hvidovre Hospital Endokrinologisk forsknings afsnit 159
RECRUITING

Hvidovre, 2650, Denmark
Institut für Diabetesforschung Osnabrück
RECRUITING

Osnabrück, 49080, Germany
Instituto de Investigaciones Clinicas San Nicolás
RECRUITING

San Nicolás, B2900, Argentina
Instituto de Investigaciones Clínicas Córdoba
RECRUITING

Córdoba, 5000, Argentina
Kiltearn Medical Centre
RECRUITING

Nantwich, CW5 5NX, United Kingdom
Knowle House Surgery
RECRUITING

Plymouth, PL5 3JB, United Kingdom
MECLINAS
RECRUITING

Mechelen, 2800, Belgium
MVZ im Altstadt-Carree Fulda GmbH - Zentrum für klinische Studien
RECRUITING

Fulda, 36037, Germany
Medical Uni of SC Charleston
RECRUITING

Charleston, South Carolina, 29425, United States
Midwest Inst For Clin Res
RECRUITING

Indianapolis, Indiana, 46260, United States
Milestone Research
RECRUITING

London, Ontario, N5W 6A2, Canada
New York Gastroenterology Associates
RECRUITING

New York, New York, 10075, United States
Nova Scotia Hlth Halifax
RECRUITING

Halifax, Nova Scotia, B3H1V7, Canada
Ocean West Research Clinic
RECRUITING

Surrey, British Columbia, V3Z 2N6, Canada
PharmQuest Life Sciences LLC
RECRUITING

Greensboro, North Carolina, 27408, United States
Pickering Medical Practice
RECRUITING

Pickering, North Yorkshire, YO18 8BL, United Kingdom
Rainier Clin Res Ctr Inc
RECRUITING

Renton, Washington, 98057, United States
SMO.MD GmbH - Zentrum für klinische Studien
RECRUITING

Magdeburg, 39120, Germany
Sanatorio Esperanza
RECRUITING

Esperanza, Santa Fe, S3080BQV, Argentina
Sanos Clinic - Gandrup
RECRUITING

Gandrup, 9362, Denmark
Sanos Clinic - Vejle
RECRUITING

Vejle, Region Syddanmark, 7100, Denmark
Selma Medical Associates
RECRUITING

Winchester, Virginia, 22601-3834, United States
South Broward Research LLC
RECRUITING

Miramar, Florida, 33027, United States
Staploe Medical Centre
RECRUITING

Soham, CB7 5JD, United Kingdom
Steno Diabetes Center Nordjylland
COMPLETED

Gistrup, 9260, Denmark
StudyMetrix Research LLC
RECRUITING

City of Saint Peters, Missouri, 63303, United States
Sydney Cardiometabolic Centre
RECRUITING

Liverpool, New South Wales, 2170, Australia
Sydney Clinical Trials
RECRUITING

Campbelltown, New South Wales, 2560, Australia
The Adam Practice
RECRUITING

Poole, Dorset, BH16 5PW, United Kingdom
The Crouch Oak Family Practice
RECRUITING

Addlestone, Surrey, KT15 2BH, United Kingdom
The Health Centre
RECRUITING

Bradford-on-Avon, BA15 1DQ, United Kingdom
UNC Eastowne Medical Office
RECRUITING

Chapel Hill, North Carolina, 27514, United States
UPA Ctr Weight and Eating Dis
RECRUITING

Philadelphia, Pennsylvania, 19104, United States
UZ Leuven - Endocrinology
RECRUITING

Leuven, 3000, Belgium
UZA - UZ Antwerpen - Department of Endocrinology
RECRUITING

Edegem, 2650, Belgium
Universitair Ziekenhuis Gent
RECRUITING

Ghent, 9000, Belgium
Velocity Clinical Res-Dallas
RECRUITING

Dallas, Texas, 75230-6855, United States
Washington Cntr Weight Mgmt
RECRUITING

Arlington, Virginia, 22206, United States
Zentrum für klinische Studien Südbrandenburg GmbH
RECRUITING

Elsterwerda, 04910, Germany

More trials for these conditions

Other studies related to the condition(s) this trial covers.