Experimental uric acid drug enters first human tests

NCT ID NCT06859073

First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study tests an experimental drug called NNC4004-0002 in 60 adults with high uric acid but no symptoms. Participants receive either the drug or a placebo as a single injection under the skin. The main goal is to check safety and how the body handles the drug, with a secondary focus on its ability to lower uric acid levels.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

NNC4004-0002 (an experimental drug given as an injection under the skin)

What this could lead to

If this drug is safe and lowers uric acid effectively, it could point toward a new treatment for high uric acid levels, potentially reducing the risk of gout or kidney stones.

What could go wrong

This is a very early (Phase 1) trial with only 60 people, so the drug may not work or could have side effects. It is the first time this drug is given to humans, so safety is still unknown.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for HEALTHY VOLUNTEERS are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

Hyperuricemia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • PAREXEL Glendale/LA EPCU

    NOT_YET_RECRUITING

    Glendale, California, 91206, United States

  • PAREXEL Intl - EPCU-Baltimore

    RECRUITING

    Baltimore, Maryland, 21225, United States