Leg heat therapy shows promise for heart failure patients
NCT ID NCT06388226
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether daily leg heat therapy can help people with heart failure with preserved ejection fraction (HFpEF) exercise longer and feel better. Participants wear water-circulating trousers heated to 42°C for 90 minutes each day at home. The goal is to see if this improves muscle function and exercise tolerance compared to a sham treatment. The study enrolls 90 adults aged 18 and older with a confirmed HFpEF diagnosis.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Leg heat therapy using water-circulating trousers heated to 42°C
What this could lead to
If it works, this could offer a simple, home-based way to improve exercise capacity and quality of life for people with heart failure with preserved ejection fraction.
What could go wrong
This is a small pilot study with only 90 participants, so results may not apply to everyone. The treatment is non-invasive and low-risk, but it may not provide meaningful improvement over the sham therapy.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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IU Health Methodist
RECRUITINGIndianapolis, Indiana, 46202, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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IU Health University Hospital
RECRUITINGIndianapolis, Indiana, 46202, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••