Could a single iron infusion ease heart failure in seniors?
NCT ID NCT07686692
First seen Jul 07, 2026 · Last updated Jul 08, 2026 · Updated 1 time
Summary
This study tests whether a single intravenous dose of iron (ferric derisomaltose) can improve symptoms, reduce hospitalizations, and boost quality of life in adults aged 65 and older who have heart failure with preserved ejection fraction and iron deficiency. Participants receive either the iron infusion or a placebo, and researchers track outcomes like survival, hospital stays, and physical function over time.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Ferric derisomaltose (intravenous iron)
- What this could lead to
- If it works, this could offer a simple infusion to improve daily function and reduce hospital stays for older adults with heart failure and low iron.
- What could go wrong
- This is a single-dose study in a specific older population; results may not apply to all heart failure patients. Iron overload or allergic reactions are possible risks.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
-
Duke University Health System
Durham, North Carolina, 27705, United States
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