HEART FAILURE WITH PRESERVED EJECTION FRACTION
Clinical trials for HEART FAILURE WITH PRESERVED EJECTION FRACTION explained in plain language.
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New heart failure drug shows promise in Mid-Stage trial
Disease control TerminatedThis study tested an investigational drug called LY3540378 in 332 adults with worsening chronic heart failure where the heart pumps normally but doesn't fill properly (HFpEF). The goal was to see if the drug could improve heart function and safety compared to a placebo. The trial…
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION
Phase: PHASE2 • Sponsor: Eli Lilly and Company • Aim: Disease control
Last updated Jun 27, 2026 09:02 UTC
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Heart failure drug trial halted early – what went wrong?
Disease control TerminatedThis small study tested a drug called PL-3994 in 15 people with a type of heart failure where the heart pumps normally but doesn't relax properly. The goal was to see if the drug improved heart function and if effects differed between men and women. The trial was terminated early…
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION
Phase: PHASE2 • Sponsor: Palatin Technologies, Inc • Aim: Disease control
Last updated Jun 27, 2026 08:04 UTC
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Heart failure drug trial ends early – only 4 patients enrolled
Disease control TerminatedThis was a very early (Phase 1) study testing a drug called HS135 in obese patients who have both pulmonary hypertension and a type of heart failure called HFpEF. The trial was terminated after enrolling only 4 people, so we have no useful information on whether HS135 is safe or …
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION
Phase: PHASE1 • Sponsor: 35Pharma Inc • Aim: Disease control
Last updated Jun 26, 2026 14:09 UTC
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Virtual exercise coach tested for heart failure – but trial stops early
Symptom relief TerminatedThis study tested a program called HEART Camp Connect, which uses a virtual coach to help adults with heart failure exercise 150 minutes per week. Only 11 people enrolled before the trial was stopped. Researchers wanted to see if the program improved exercise habits and heart-rel…
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION
Phase: NA • Sponsor: University of Nebraska • Aim: Symptom relief
Last updated Jun 27, 2026 08:03 UTC
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Hidden heart condition: study seeks to uncover missed diagnosis in heart failure patients
Knowledge-focused TerminatedThis study aims to find out how common transthyretin amyloidosis cardiomyopathy (ATTR-CM) is in Russian patients with a certain type of heart failure. Researchers will review medical records and then invite some patients for extra heart tests to confirm or rule out ATTR-CM. The g…
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION
Sponsor: AstraZeneca • Aim: Knowledge-focused
Last updated Jun 26, 2026 17:47 UTC