HEART FAILURE WITH PRESERVED EJECTION FRACTION
Clinical trials for HEART FAILURE WITH PRESERVED EJECTION FRACTION explained in plain language.
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Heart repair drug trial halted before first patient
Disease control TerminatedThis study aimed to test whether an experimental drug called CDR132L could help improve the structure and function of the heart in people with a specific type of heart failure where the heart pumps normally but is stiff and thickened. The trial planned to enroll about 130 patient…
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION
Phase: PHASE2 • Sponsor: Cardior Pharmaceuticals GmbH • Aim: Disease control
Last updated Mar 30, 2026 14:34 UTC
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New drug trial aims to break vicious cycle in heart failure
Disease control OngoingThis study is testing whether a drug called enavogliflozin can help people who have heart failure along with a leaky tricuspid heart valve. About 541 participants will take the drug or a placebo for 18 months to see if it reduces serious heart-related events, hospital visits, or …
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION
Phase: PHASE3 • Sponsor: Asan Medical Center • Aim: Disease control
Last updated Mar 27, 2026 12:38 UTC
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New drug trial aims to ease heart failure and shed pounds
Disease control OngoingThis study is testing whether an investigational injection called HRS9531 can help control heart failure symptoms and reduce body weight in adults with obesity. About 200 participants with a specific type of heart failure were randomly assigned to receive either the real injectio…
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION
Phase: PHASE2 • Sponsor: Fujian Shengdi Pharmaceutical Co., Ltd. • Aim: Disease control
Last updated Mar 24, 2026 12:02 UTC
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New hope for stubborn heart condition? drug trial targets double trouble
Disease control OngoingThis study is testing if adding the medication sacubitril-valsartan to standard care helps people with a specific type of heart failure (where the heart pumps normally but doesn't relax well) who also have a leaky mitral valve. About 84 participants will be randomly assigned to r…
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION
Phase: PHASE4 • Sponsor: Ziekenhuis Oost-Limburg • Aim: Disease control
Last updated Mar 02, 2026 15:25 UTC
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Can exercise ease the strain of heart failure?
Symptom relief OngoingThis study is testing if a 12-week supervised exercise program can help Veterans with a specific type of heart failure (HFpEF) feel less tired and be able to do more physical activity. Researchers are looking at how nerves in the legs might contribute to exercise problems and if …
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION
Phase: NA • Sponsor: VA Office of Research and Development • Aim: Symptom relief
Last updated Mar 27, 2026 12:38 UTC
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Common diabetes drug may ease heart failure struggle
Symptom relief OngoingThis study is testing if metformin, a medication commonly used for diabetes, can help older adults with a specific type of heart failure feel better. Researchers will give 86 participants either metformin or a placebo pill for 20 weeks to see if it improves their ability to exerc…
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION
Phase: PHASE2 • Sponsor: Wake Forest University Health Sciences • Aim: Symptom relief
Last updated Mar 23, 2026 15:17 UTC
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Scientists launch major registry to unlock secrets of a common heart condition
Knowledge-focused OngoingThis study aims to create a detailed registry of 240 patients hospitalized with a specific type of heart failure where the heart pumps normally but doesn't fill properly (HFpEF). Researchers will collect extensive information on patients' health, treatments, and body measurements…
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION
Sponsor: National Medical Research Center for Therapy and Preventive Medicine • Aim: Knowledge-focused
Last updated Apr 01, 2026 14:41 UTC
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Seniors test own heart meds in personal experiment
Knowledge-focused ENROLLING_BY_INVITATIONThis study is testing a personalized approach to help older adults with a common type of heart failure decide whether to continue taking their beta-blocker medication. Researchers will work with 20 participants, having each person try periods on and off their prescribed beta-bloc…
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION
Phase: PHASE4 • Sponsor: Weill Medical College of Cornell University • Aim: Knowledge-focused
Last updated Mar 27, 2026 12:38 UTC
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Scientists test heart Drugs' hidden effects on kidneys
Knowledge-focused ENROLLING_BY_INVITATIONThis study aims to understand how two different heart failure drugs affect the body's salt and fluid balance in people who have both heart failure and kidney disease. It will involve 60 participants who will try both drugs and a placebo in a random order. Researchers will closely…
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION
Phase: PHASE1, PHASE2 • Sponsor: Horng Chen • Aim: Knowledge-focused
Last updated Mar 23, 2026 15:16 UTC