Ultrasound zaps lung nerves to ease heart failure symptoms
NCT ID NCT06052072
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This early study is testing a device that uses ultrasound to ablate (calm) nerves in the pulmonary artery. The goal is to see if this procedure can improve quality of life for 50 people with heart failure and a specific type of pulmonary hypertension (Group 2). Participants will be followed for safety and changes in blood vessel resistance.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Gradient Denervation System (ultrasound ablation device)
What this could lead to
If it works, this could offer a new way to manage heart failure and pulmonary hypertension, potentially improving daily life and reducing symptoms.
What could go wrong
This is a very early, small feasibility study with only 50 participants. The procedure carries risks like serious adverse events, and it is not yet known if it will provide lasting benefit.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for HEART FAILURE are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Locations
-
Aurora Health
Milwaukee, Wisconsin, 53215, United States
-
Baylor College of Medicine
Houston, Texas, 77030, United States
-
Duke University
Durham, North Carolina, 27708, United States
-
Houston Methodist
Houston, Texas, 77030, United States
-
Massachusetts General Hospital
Boston, Massachusetts, 02114, United States
-
Medical University of South Carolina
Charleston, South Carolina, 29425, United States
-
Northwestern University
Chicago, Illinois, 60611, United States
-
University of Wisconsin
Madison, Wisconsin, 53705, United States