Exercise may unlock better stamina for heart failure patients
NCT ID NCT04506606
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at why Veterans with heart failure with preserved ejection fraction (HFpEF) get tired so easily during exercise. Researchers will block nerve signals from leg muscles to see how that affects blood flow and fatigue, both before and after a regular exercise program. The goal is to understand if exercise can be a helpful treatment for these patients.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this could show that exercise is a valid treatment to improve exercise tolerance and quality of life in Veterans with HFpEF.
What could go wrong
This is a small, early-stage study (45 participants) focused on understanding mechanisms, not proving a treatment works. Results may not apply to all HFpEF patients.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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VA Salt Lake City Health Care System, Salt Lake City, UT
Salt Lake City, Utah, 84148-0001, United States