Can a tailored trial help heart patients decide on Beta-Blockers?
NCT ID NCT05585125
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether a personalized 'N-of-1' trial can help older adults with a type of heart failure (HFpEF) decide if they want to continue or stop taking beta-blockers. Twenty participants will go through periods on and off their beta-blocker, in a random order, to see how it affects their confidence and decision-making. The goal is to find a practical way to optimize medications for each individual.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- beta blocker (acebutolol, atenolol, betaxolol, bisoprolol, carvedilol, labetalol, metoprolol)
- What this could lead to
- If successful, this could show that personalized N-of-1 trials help patients and doctors make better decisions about continuing or stopping beta-blockers.
- What could go wrong
- This is a very small, early-phase study with only 20 participants, focused on decision-making rather than health outcomes. Results may not apply to everyone with heart failure.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Weill Cornell Medicine
New York, New York, 10065, United States
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