Could a diabetes drug ease two heart conditions at once?

NCT ID NCT06027307

First seen Jan 04, 2026 · Last updated May 12, 2026 · Updated 24 times

Summary

This study tests a drug called enavogliflozin in 541 adults with heart failure and a leaky heart valve (tricuspid regurgitation). Participants take the drug or a placebo for 18 months. The goal is to see if the drug lowers the risk of heart-related death, hospital stays, or worsening of the valve leak. This is a phase 3 trial, meaning it is in the final testing stage before possible approval.

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Contacts and locations

Locations

  • Asan Medical Center

    Seoul, South Korea

  • Inha University Hospital

    Incheon, South Korea

  • Samsung Medical Center

    Seoul, South Korea

  • Seoul National University Hospital

    Seoul, South Korea

  • Yonsei University Medical Center

    Seoul, South Korea

Conditions

Explore the condition pages connected to this study.