HEART FAILURE WITH PRESERVED EJECTION FRACTION
Clinical trials for HEART FAILURE WITH PRESERVED EJECTION FRACTION explained in plain language.
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Can a common heart drug reverse scarring in stiff heart failure?
Disease control Not yet recruitingThis study looks at whether the drug sacubitril/valsartan can reduce scarring in the heart muscle of people with a type of heart failure called HFpEF (stiff heart). About 36 adults aged 50 and older will get either the study drug or a similar drug alone. Researchers will use MRI …
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION
Phase: PHASE4 • Sponsor: Brigham and Women's Hospital • Aim: Disease control
Last updated May 17, 2026 02:08 UTC
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New heart procedure could reduce hospital stays for heart failure patients
Disease control Not yet recruitingThis study tests a procedure called pulmonary artery denervation (PADN) combined with standard medications versus a sham procedure with medications in 310 heart failure patients with preserved ejection fraction. The goal is to see if PADN reduces the risk of death, heart failure-…
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION
Phase: NA • Sponsor: Nanjing First Hospital, Nanjing Medical University • Aim: Disease control
Last updated May 17, 2026 02:04 UTC
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New study tests if a heart procedure can save lives in patients with both AF and heart failure
Disease control Not yet recruitingThis study looks at 900 adults with atrial fibrillation (an irregular heartbeat) and a type of heart failure where the heart's pumping ability is mildly reduced or preserved. It compares a procedure called catheter ablation (which destroys tiny areas of heart tissue causing the i…
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION
Phase: NA • Sponsor: Tulane University • Aim: Disease control
Last updated May 15, 2026 11:57 UTC
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New device zaps lung arteries to ease heart failure
Disease control Not yet recruitingThis study tests a device that uses radiofrequency energy to treat high blood pressure in the lungs of people with heart failure. The treatment aims to reduce serious heart events like hospitalizations or death. About 750 adults with stable heart failure will be randomly assigned…
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION
Phase: NA • Sponsor: Pulnovo Medical, Inc. • Aim: Disease control
Last updated May 13, 2026 15:58 UTC
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Heart failure drug trial aims to boost stamina and brain power
Symptom relief Not yet recruitingThis study tests an experimental drug (activin ligand-trap) combined with exercise training in 48 adults with a common type of heart failure (HFpEF). The goal is to see if the drug can improve how much oxygen the body uses during exercise and also sharpen thinking skills. Partici…
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION
Phase: PHASE2 • Sponsor: Massachusetts General Hospital • Aim: Symptom relief
Last updated May 15, 2026 11:53 UTC
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Can group exercise and remote tracking help heart failure patients feel better?
Symptom relief Not yet recruitingThis study tests a new group exercise program combined with remote activity monitoring for older adults with heart failure with preserved ejection fraction (HFpEF). The goal is to see if this approach can improve exercise habits, physical function, and quality of life. About 14 p…
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION
Phase: NA • Sponsor: Wake Forest University Health Sciences • Aim: Symptom relief
Last updated May 04, 2026 16:21 UTC
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New study probes Tirzepatide's heart benefits in Obesity-Related heart failure
Knowledge-focused Not yet recruitingThis study looks at how tirzepatide, a diabetes drug, helps people with obesity and a type of heart failure called HFpEF. Researchers will measure blood volume and body fat in 50 patients over 15 months to understand how the drug works. The goal is to find out if tirzepatide redu…
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION
Phase: PHASE4 • Sponsor: Columbia University • Aim: Knowledge-focused
Last updated May 17, 2026 02:02 UTC