HEART FAILURE WITH PRESERVED EJECTION FRACTION
Clinical trials for HEART FAILURE WITH PRESERVED EJECTION FRACTION explained in plain language.
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Could a single iron infusion ease heart failure in seniors?
Disease control Not yet recruitingThis study tests whether a single intravenous dose of iron (ferric derisomaltose) can improve symptoms, reduce hospitalizations, and boost quality of life in adults aged 65 and older who have heart failure with preserved ejection fraction and iron deficiency. Participants receive…
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION
Phase: PHASE4 • Sponsor: Duke University • Aim: Disease control
Last updated Jul 09, 2026 00:00 UTC
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New study to see if heart procedure beats standard care for AF and heart failure
Disease control Not yet recruitingThis study compares a heart procedure called catheter ablation to standard medical treatment for people with atrial fibrillation (an irregular heartbeat) and heart failure with preserved ejection fraction (a type of heart failure where the heart pumps normally but is stiff). The …
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION
Phase: NA • Sponsor: Tulane University • Aim: Disease control
Last updated Jun 27, 2026 14:00 UTC
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Weight-Loss drug mounjaro could keep hearts in rhythm after ablation
Disease control Not yet recruitingThis study tests whether the diabetes and weight-loss drug tirzepatide (Mounjaro) can reduce the chance of atrial fibrillation coming back after a heart procedure called catheter ablation. About 602 adults with obesity and a type of heart failure (HFpEF) will get either tirzepati…
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION
Phase: PHASE4 • Sponsor: Yunlong Wang • Aim: Disease control
Last updated Jun 27, 2026 13:02 UTC
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Could a gut bacteria transplant ease heart failure in seniors?
Disease control Not yet recruitingThis study tests whether transplanting healthy gut bacteria (fecal microbiota transplantation) can improve quality of life and exercise ability in elderly patients with a common type of heart failure (HFpEF). Fifty adults aged 60 and older will receive either the transplant or a …
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION
Phase: PHASE1, PHASE2 • Sponsor: The First Affiliated Hospital of Air Force Medicial University • Aim: Disease control
Last updated Jun 27, 2026 13:02 UTC
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New procedure targets nerves to treat stubborn heart failure
Disease control Not yet recruitingThis study tests a procedure called pulmonary artery denervation (PADN) for people with heart failure whose heart pumps normally but is stiff. The procedure uses a catheter to burn nerves in the lung artery, which may help the heart work better. About 310 participants will either…
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION
Phase: NA • Sponsor: Nanjing First Hospital, Nanjing Medical University • Aim: Disease control
Last updated Jun 27, 2026 12:37 UTC
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Can a pill reverse heart scarring? new study aims to find out
Disease control Not yet recruitingThis study tests whether the drug finerenone can reduce scarring in the heart muscle and improve heart structure and function in people with heart failure. About 104 adults with mild to moderate heart failure will receive either finerenone or a placebo for 6 months. The main goal…
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION
Phase: PHASE4 • Sponsor: China National Center for Cardiovascular Diseases • Aim: Disease control
Last updated Jun 27, 2026 12:33 UTC
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Could mounjaro ease heart failure in obesity? new trial investigates
Disease control Not yet recruitingThis study will test whether tirzepatide (Mounjaro), a drug used for diabetes and weight loss, can help people with obesity-related heart failure with preserved ejection fraction (HFpEF). Researchers will measure changes in blood volume and body fat in 50 participants over 15 mon…
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION
Phase: PHASE4 • Sponsor: Columbia University • Aim: Disease control
Last updated Jun 27, 2026 12:29 UTC
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Can a common heart drug reverse scarring in stiff heart failure?
Disease control Not yet recruitingThis study tests whether the drug sacubitril/valsartan can reduce scarring in the heart muscle of people with a type of heart failure called HFpEF (stiff heart). The trial will enroll 36 adults aged 50 and older with heart failure and a normal pumping function. Participants will …
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION
Phase: PHASE4 • Sponsor: Brigham and Women's Hospital • Aim: Disease control
Last updated Jun 27, 2026 09:08 UTC
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Stiff arteries may hold key to heart failure progression
Knowledge-focused Not yet recruitingThis study looks at how the stiffness and function of blood vessels change in people newly diagnosed with heart failure. Researchers will measure these factors at the start, after a few weeks of standard medication, and after a cardiac rehab program. All tests are non-invasive an…
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION
Sponsor: Coventry University • Aim: Knowledge-focused
Last updated Jul 22, 2026 00:00 UTC
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Jardiance under the microscope: new study tracks heart failure outcomes in china
Knowledge-focused Not yet recruitingThis study will observe 3,000 adults in China with a type of heart failure called HFpEF who are starting the drug Jardiance. Researchers will track how many patients are hospitalized for heart failure or die from heart-related causes over time. The goal is to see how effective an…
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION
Sponsor: Boehringer Ingelheim • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:05 UTC