Can a common heart drug reverse scarring in stiff heart failure?

NCT ID NCT06536309

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether the drug sacubitril/valsartan can reduce scarring in the heart muscle of people with a type of heart failure called HFpEF (stiff heart). The trial will enroll 36 adults aged 50 and older with heart failure and a normal pumping function. Participants will receive either the study drug or a comparison drug (valsartan alone) for one year, and heart scarring will be measured using MRI scans.

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Conditions

The condition(s) this trial relates to.

diastolic heart failure endomyocardial fibrosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••