MYOCARDIAL FIBROSIS
Clinical trials for MYOCARDIAL FIBROSIS explained in plain language.
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Triple drug combo aims to reverse heart scarring in stiff heart failure
Disease control Recruiting nowThis study tests whether a three-drug combination (SGLT2 inhibitor, ARNI, and MRA) can improve heart structure, function, and symptoms in 50 people with advanced HFpEF, a type of heart failure where the heart is stiff but pumps normally. Participants will receive either the tripl…
Matched conditions: MYOCARDIAL FIBROSIS
Phase: PHASE2 • Sponsor: National Medical Research Center for Cardiology, Ministry of Health of Russian Federation • Aim: Disease control
Last updated Jun 27, 2026 12:23 UTC
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Gene therapy trial aims to fix heart damage in rare disease
Disease control Recruiting nowThis early-stage trial tests a gene therapy called AAVrh.10hFXN for heart problems caused by Friedreich's ataxia, a rare genetic disease. The therapy delivers a working copy of the frataxin gene to help heart cells function better. 25 people aged 12 to 50 with heart involvement w…
Matched conditions: MYOCARDIAL FIBROSIS
Phase: PHASE1 • Sponsor: Weill Medical College of Cornell University • Aim: Disease control
Last updated Jun 27, 2026 12:02 UTC
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New contrast agent could mean lower doses for heart MRI
Diagnosis Recruiting nowThis study tests whether a new MRI contrast agent called Elucirem can detect heart scarring as effectively as the standard agent, but at a much lower dose. Researchers will compare images from 25 adults who previously had a heart MRI with the standard agent. If Elucirem works wel…
Matched conditions: MYOCARDIAL FIBROSIS
Phase: PHASE4 • Sponsor: Johns Hopkins University • Aim: Diagnosis
Last updated Jun 27, 2026 12:06 UTC
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Heart MRI breakthrough could spot hidden risks in thousands
Knowledge-focused Recruiting nowThis study is testing whether a detailed heart MRI (called T1 mapping) can better predict who will develop heart disease, heart failure, or long COVID complications. Researchers will scan 6000 adults without known heart disease and follow them over time. The goal is to see if sub…
Matched conditions: MYOCARDIAL FIBROSIS
Sponsor: Johann Wolfgang Goethe University Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:08 UTC
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New PET scan could reveal hidden heart scarring in real time
Knowledge-focused Recruiting nowThis pilot study is testing a new type of PET/CT scan that uses a radioactive tracer called 68Ga-FAPI to detect active scarring (fibrosis) in the hearts of 30 people with heart failure. The goal is to see if this scan can spot early or ongoing scarring better than current MRI met…
Matched conditions: MYOCARDIAL FIBROSIS
Sponsor: University of Coimbra • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:07 UTC