New contrast agent could mean lower doses for heart MRI

NCT ID NCT05954559

First seen Apr 23, 2026

Summary

This study tests whether a new MRI contrast agent called Elucirem can detect heart scarring as effectively as the standard agent, but at a much lower dose. Researchers will compare images from 25 adults who previously had a heart MRI with the standard agent. If Elucirem works well at half the usual dose, it could mean less contrast agent exposure for patients.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Johns Hopkins Center for Advanced Imaging and Research Science, located in the Science + Technology Park at 1812 Ashland Avenue, Baltimore, MD.

    RECRUITING

    Baltimore, Maryland, 21202, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Johns Hopkins School of Medicine

    NOT_YET_RECRUITING

    Baltimore, Maryland, 21205, United States

    Contact Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Elucirem (Gadopiclenol)

What this could lead to

If successful, this could allow doctors to use a lower dose of contrast agent for heart MRI, potentially reducing risks while still accurately detecting heart scarring.

What could go wrong

This is a very small, early-phase study with only 25 participants. The new agent may not perform as well as the standard one at lower doses, and results may not apply to all patients.

Conditions

The condition(s) this trial relates to.

endomyocardial fibrosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.