Blood pressure drug may shield hearts during breast cancer radiation
NCT ID NCT05607017
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This early-phase study tested whether losartan, a common blood pressure medication, could prevent early heart damage caused by radiation therapy in breast cancer patients. Five women with left-sided breast cancer who were scheduled for radiation took losartan. Researchers used heart MRIs to measure changes in heart tissue. The goal was to see if losartan could reduce the risk of future heart failure.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Losartan
What this could lead to
If it works, this could point toward a way to prevent heart failure in breast cancer patients receiving radiation therapy.
What could go wrong
This is a very early, tiny trial with only 5 participants, so results may not be reliable or apply to others. It only looked at early heart changes, not actual heart failure.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Massachusetts General Hospital Cancer Center
Boston, Massachusetts, 02114, United States