MYOCARDIAL FIBROSIS
Clinical trials for MYOCARDIAL FIBROSIS explained in plain language.
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New triple therapy aims to reverse heart damage in stiff heart condition
Disease control Recruiting nowThis study tests whether a combination of three heart medications (SGLT2 inhibitor, ARNI, and MRA) can improve heart structure, function, and daily life in people with advanced heart failure with preserved ejection fraction (HFpEF). Fifty participants will receive either the trip…
Matched conditions: MYOCARDIAL FIBROSIS
Phase: PHASE2 • Sponsor: National Medical Research Center for Cardiology, Ministry of Health of Russian Federation • Aim: Disease control
Last updated May 17, 2026 05:32 UTC
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First-in-Human gene therapy trial targets devastating heart condition
Disease control Recruiting nowThis is an early-stage study testing the safety of a new gene therapy for the heart damage caused by Friedreich's ataxia. The therapy uses a modified virus to deliver a healthy gene directly to the heart. Researchers will enroll 25 participants to find a safe dose and look for ea…
Matched conditions: MYOCARDIAL FIBROSIS
Phase: PHASE1 • Sponsor: Weill Medical College of Cornell University • Aim: Disease control
Last updated Apr 09, 2026 19:33 UTC
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New heart scan dye uses half the dose
Diagnosis Recruiting nowThis study is testing a new, FDA-approved MRI contrast dye called Elucirem to see if it can detect scarring in heart muscle as well as a standard dye, but using only half the dose. Researchers will compare new scans using Elucirem with old scans from the same 25 participants who …
Matched conditions: MYOCARDIAL FIBROSIS
Phase: PHASE4 • Sponsor: Johns Hopkins University • Aim: Diagnosis
Last updated Apr 23, 2026 12:44 UTC
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Can a new PET scan spot hidden heart damage?
Knowledge-focused Recruiting nowThis study tests a new type of PET/CT scan (68Ga-FAPI) to see if it can detect active scarring in the heart muscle of people with heart failure. Researchers will compare this scan with standard MRI to find out if it can spot early or ongoing fibrosis that current methods miss. Th…
Matched conditions: MYOCARDIAL FIBROSIS
Sponsor: University of Coimbra • Aim: Knowledge-focused
Last updated May 17, 2026 05:31 UTC
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6,000 volunteers needed for landmark heart MRI study
Knowledge-focused Recruiting nowThis study aims to improve how doctors predict heart disease risk by using advanced MRI scans (T1 mapping) of the heart. Researchers will enroll 6,000 adults without known heart disease, including people with Long COVID, to establish normal ranges and see if these scans can detec…
Matched conditions: MYOCARDIAL FIBROSIS
Sponsor: Johann Wolfgang Goethe University Hospital • Aim: Knowledge-focused
Last updated May 15, 2026 11:57 UTC