New PET scan could reveal hidden heart scarring in real time

NCT ID NCT07296081

Recruiting now Knowledge-focused Sponsor: University of Coimbra Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This pilot study is testing a new type of PET/CT scan that uses a radioactive tracer called 68Ga-FAPI to detect active scarring (fibrosis) in the hearts of 30 people with heart failure. The goal is to see if this scan can spot early or ongoing scarring better than current MRI methods. If it works, it could help doctors monitor disease and guide future treatments.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: 68Ga-FAPI (a radioactive tracer for PET/CT scans)
What this could lead to: If successful, this scan could help doctors see active heart scarring in real time, guiding anti-fibrotic treatments and improving heart failure management.
What could go wrong: This is a very small, early pilot study with only 30 participants. The new scan may not prove better than existing methods, and results may not apply to all heart failure patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

dilated cardiomyopathy endomyocardial fibrosis heart failure hypertrophic cardiomyopathy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HEART FAILURE MYOCARDIAL FIBROSIS

Contacts and locations

Locations

Faculdade de Medicina da Universidade de Coimbra
RECRUITING

Coimbra, Coimbra District, 3000-548, Portugal

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