HEART FAILURE WITH PRESERVED EJECTION FRACTION
Clinical trials for HEART FAILURE WITH PRESERVED EJECTION FRACTION explained in plain language.
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HIV heart shield: hormone therapy may stop silent failure
Disease control CompletedThis study tested whether blocking the hormone aldosterone and boosting another hormone called BNP could reduce early heart damage in people with HIV. 39 participants with well-controlled HIV and signs of early heart stress received the treatment. The goal was to see if this appr…
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION
Phase: PHASE2 • Sponsor: Massachusetts General Hospital • Aim: Disease control
Last updated May 11, 2026 20:38 UTC
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Could a common diabetes pill ease rare heart condition?
Disease control CompletedThis study tested the drug dapagliflozin (a diabetes medicine) in 50 adults with heart failure due to amyloid cardiomyopathy, a rare condition where abnormal proteins stiffen the heart. Researchers measured changes in quality of life, walking ability, and heart stress levels over…
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION
Phase: NA • Sponsor: National Medical Research Center for Cardiology, Ministry of Health of Russian Federation • Aim: Disease control
Last updated May 11, 2026 20:37 UTC
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New MRI test may detect rare heart disease without a biopsy
Diagnosis CompletedThis study tested a special heart MRI technique called T1 mapping to see if it can accurately diagnose cardiac amyloidosis, a condition where abnormal proteins build up in the heart. Researchers studied 112 older adults with heart failure and thickened heart walls. The goal was t…
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION
Sponsor: University of Leipzig • Aim: Diagnosis
Last updated May 13, 2026 16:01 UTC
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Sleep more, feel better? pilot study tests sleep extension for heart failure patients
Symptom relief CompletedThis small pilot study tested whether gradually extending sleep time, combined with good sleep habits, is possible and can improve quality of life in people with a type of heart failure called HFpEF. Ten adults with heart failure who slept less than 7 hours a night and had poor s…
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION
Phase: NA • Sponsor: Virginia Commonwealth University • Aim: Symptom relief
Last updated May 17, 2026 05:45 UTC
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Heart rehab boosts mobility in seniors with heart failure
Symptom relief CompletedThis study looked at whether a 12-week cardiac rehabilitation program can improve movement, breathing, and heart function in people aged 70 and older with heart failure. 65 participants were randomly assigned to the program or a control group. The goal was to see if exercise and …
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION
Phase: NA • Sponsor: University of Malaga • Aim: Symptom relief
Last updated May 17, 2026 05:44 UTC
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Gut health boost may help heart failure patients move more
Symptom relief CompletedThis study tested whether taking a probiotic called Lactobacillus plantarum 299v for 12 weeks could improve exercise capacity and blood vessel function in people with chronic heart failure. Ten adults with heart failure and signs of inflammation took either the probiotic or a pla…
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION
Phase: NA • Sponsor: Medical College of Wisconsin • Aim: Symptom relief
Last updated May 17, 2026 05:33 UTC
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Diabetes drug shows promise for heart failure patients
Symptom relief CompletedThis study tested whether metformin, a common diabetes medication, can improve exercise ability and quality of life in older adults with heart failure with preserved ejection fraction (HFpEF). 86 participants took either metformin or a placebo for 20 weeks. Researchers measured o…
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION
Phase: PHASE2 • Sponsor: Wake Forest University Health Sciences • Aim: Symptom relief
Last updated May 13, 2026 15:59 UTC
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Heart failure breakthrough? study tests best blood pressure drug combo
Symptom relief CompletedThis study looked at 50 adults with heart failure (a condition where the heart doesn't pump blood well) and high blood pressure. Researchers compared two common blood pressure drugs—calcium channel blockers and beta-blockers—to see which one works better at lowering blood pressur…
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION
Phase: PHASE4 • Sponsor: University of Pennsylvania • Aim: Symptom relief
Last updated May 11, 2026 20:39 UTC
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Sleep apnea device study reveals impact on rest
Knowledge-focused CompletedThis study followed 520 French adults with central or mixed sleep apnea to see how a treatment called adaptive servo-ventilation (ASV) improves sleep quality. Participants used the ASV device at night, and researchers measured sleep quality changes over time. The study excluded p…
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION
Sponsor: Société Française de Recherche et de Médecine du Sommeil • Aim: Knowledge-focused
Last updated May 17, 2026 05:37 UTC
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Heart fat linked to pump function in major heart failure study
Knowledge-focused CompletedThis study looked at how fat around the heart (epicardial fat) is related to heart function in people with a specific type of heart failure called HFpEF. Researchers measured the fat thickness and heart function using ultrasound in over 1,000 adults with HFpEF. The goal was to be…
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION
Sponsor: Dongying Zhang • Aim: Knowledge-focused
Last updated May 17, 2026 05:33 UTC