Heart drug combo shows promise for stiff heart and leaky valve

NCT ID NCT05991284

First seen Jan 05, 2026 · Last updated Jun 17, 2026 · Updated 25 times

Summary

This study looked at whether adding sacubitril-valsartan to standard care helps people with a type of heart failure where the heart pumps normally but is stiff, and who also have a leaky mitral valve. 84 adults took either the extra medication or standard care alone for six months. The goal was to see if the drug improves heart function during exercise and reduces symptoms.

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Contacts and locations

Locations

  • Ziekenhuis Oost-Limburg

    Genk, 3600, Belgium

Conditions

Explore the condition pages connected to this study.