New hope for heart failure patients with leaky valves?

NCT ID NCT05991284

First seen Jan 05, 2026 · Last updated Apr 30, 2026 · Updated 16 times

Summary

This study looks at whether adding the drug sacubitril-valsartan to standard care can improve heart function in people with a type of heart failure (preserved ejection fraction) and at least moderate mitral valve leakage. About 84 adults will be randomly assigned to get the drug or continue standard care alone. The main goal is to measure changes in heart pressure and oxygen use during exercise after six months of treatment.

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Contacts and locations

Locations

  • Ziekenhuis Oost-Limburg

    Genk, 3600, Belgium

Conditions

Explore the condition pages connected to this study.