Simple stress echo upgrade may spot hidden stiff heart

NCT ID NCT06927973

Completed Diagnosis Sponsor: Duke University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at whether taking extra ultrasound images during a standard stress echocardiogram can help doctors figure out if chest pain or shortness of breath is caused by a stiff heart (heart failure with preserved ejection fraction, or HFpEF). Researchers enrolled 30 people aged 50 and older who were already scheduled for a stress echo. They compared the extra images and a risk score to standard care to see if it improved diagnosis.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could improve how doctors diagnose stiff heart (HFpEF) using a simple stress echo, reducing the need for more invasive tests.
What could go wrong: This is a small, completed study (30 people) focused on diagnosis, not treatment. The results may not apply to everyone, and the added images might not clearly improve diagnosis.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Chest Pain diastolic heart failure Dyspnea

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CHEST PAIN SHORTNESS OF BREATH

Contacts and locations

Locations

Duke University Medical Center

Durham, North Carolina, 27710, United States

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