Heart failure drug shows promise for Non-Diabetics

NCT ID NCT07112274

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This completed study tested whether empagliflozin, a diabetes drug, can improve heart structure and function in 50 non-diabetic patients with heart failure with preserved ejection fraction. Participants took either empagliflozin or a placebo daily. Researchers measured heart stress markers to see if the drug helps reduce cardiac remodeling.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

empagliflozin (10 mg tablet once daily)

What this could lead to

If successful, this could point toward a new treatment option for heart failure patients who are not diabetic, potentially improving heart function and quality of life.

What could go wrong

This is a small, completed trial with only 50 participants, so results may not apply to everyone. The study measured biomarkers, not long-term outcomes, so real-world benefits are uncertain.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

diastolic heart failure heart failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Rehab Hussein Werida

    Damanhūr, Elbehairah, 31527, Egypt