Can a beta-blocker help a common type of heart failure? new study investigates.

NCT ID NCT05553314

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether a slow-release form of the beta-blocker carvedilol can improve heart function in people with heart failure with preserved ejection fraction (HFpEF), a condition where the heart pumps normally but is too stiff. 63 adults with high blood pressure and signs of heart strain took either the drug or a placebo for 6 months. Researchers measured changes in a blood marker (NT-proBNP) and heart muscle strain (GLS) to see if the drug helps.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Samsung Medical Center

    Seoul, Il-won, 06351, South Korea

  • Wonju Severance Christian Hospital

    Wŏnju, WONJU, 26426, South Korea

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Other studies related to the condition(s) this trial covers.