New study tests heart failure drugs in patients with kidney problems

NCT ID NCT05279742

ENROLLING_BY_INVITATION Knowledge-focused Sponsor: Horng Chen Source: ClinicalTrials.gov ↗

First seen Nov 01, 2025 · Last updated May 15, 2026 · Updated 22 times

Summary

This study looks at how two drugs, Sacubitril/Valsartan (Entresto) and MANP, affect people with a type of heart failure called HFpEF, which also involves chronic kidney disease or shortness of breath during exercise. Researchers will measure changes in body fluids and certain chemicals to understand how these drugs work. The study involves 60 adults and aims to gather information rather than provide direct treatment.

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Contacts and locations

Locations

  • Mayo Clinic in Rochester

    Rochester, Minnesota, 55905, United States

Conditions

Explore the condition pages connected to this study.