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Hidden heart condition: study seeks to uncover missed diagnosis in heart failure patients

NCT ID NCT06338839

Terminated Knowledge-focused Sponsor: AstraZeneca Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study aims to find out how common transthyretin amyloidosis cardiomyopathy (ATTR-CM) is in Russian patients with a certain type of heart failure. Researchers will review medical records and then invite some patients for extra heart tests to confirm or rule out ATTR-CM. The goal is to better understand this underdiagnosed condition in real-world medical practice.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this study could help doctors better identify a hidden cause of heart failure, leading to earlier diagnosis and more targeted care.
What could go wrong
This is an observational study, not a treatment trial, so it won't directly help patients. It was also terminated early, which may limit the data collected.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

ATTRV122I amyloidosis diastolic heart failure wild type ATTR amyloidosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

TRANSTHYRETIN AMYLOIDOSIS CARDIOMYOPATHY, HEART FAILURE WITH PRESERVED EJECTION FRACTION

Contacts and locations

Locations

  • Research Site

    Akhtubinsk, Russia

  • Research Site

    Astrakhan, Russia

  • Research Site

    Barnaul, Russia

  • Research Site

    Beslan, Russia

  • Research Site

    Chelyabinsk, Russia

  • Research Site

    Izhevsk, Russia

  • Research Site

    Kaluga, Russia

  • Research Site

    Kazan', Russia

  • Research Site

    Khabarovsk, Russia

  • Research Site

    Kirov, Russia

  • Research Site

    Krasnodar, Russia

  • Research Site

    Nizhny Novgorod, Russia

  • Research Site

    Omsk, Russia

  • Research Site

    Rostov-on-Don, Russia

  • Research Site

    Smolensk, Russia

  • Research Site

    Ufa, Russia

  • Research Site

    Vladimir, Russia

  • Research Site

    Vladivostok, Russia

  • Research Site

    Volgograd, Russia

  • Research Site

    Yaroslavl, Russia

  • Research Site

    Yekaterinburg, Russia

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