New electric pulse procedure could tame AFib in heart failure patients
NCT ID NCT07385417
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This pilot study is testing a new procedure called electroporation ablation (using the FARAPULSE system) to treat atrial fibrillation in 200 people who also have heart failure with preserved ejection fraction. Half will get the procedure, half will get standard medical care. The goal is to see if the procedure reduces hospitalizations, strokes, and other serious events. The study is currently recruiting.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- electroporation ablation (FARAPULSE procedure)
- What this could lead to
- If successful, this could offer a more effective way to control atrial fibrillation in people with heart failure, potentially reducing hospital visits and complications.
- What could go wrong
- This is a small, early pilot study, so results may not apply broadly. The procedure carries risks like bleeding, nerve injury, or heart damage, and it's unclear if it will outperform standard medication.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for ATRIAL FIBRILLATION (AF) are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Cardioangiologisches Centrum Bethanien
RECRUITINGFrankfurt am Main, 60431, Germany
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can shedding pounds reboot the Heart's exercise engine?
- Could a smartphone alert replace daily blood thinners for AF?
- Blood fat clues could flag hidden heart rhythm risk
- Could a bigger balloon tame the Heart's electrical chaos?
- Can a new heart ablation technique work without x-rays?
- Which blood thinner is safer for heart patients? a Head-to-Head test