Could ditching Beta-Blockers improve heart function?
NCT ID NCT05174351
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looks at what happens when people with a certain type of heart failure (HFpEF) stop taking beta-blockers for 4 weeks. Researchers will measure changes in heart function, exercise ability, and quality of life in 30 participants. The goal is to see if stopping this common medication might actually be beneficial for these patients.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
beta blocker discontinuation
What this could lead to
If successful, this could suggest that some HFpEF patients may do better without beta-blockers, pointing toward a change in treatment guidelines.
What could go wrong
This is a very small pilot study with only 30 participants and no control group. Results may not apply to all HFpEF patients, and stopping beta-blockers could worsen symptoms in some individuals.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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UConn Health / John Dempsey Hospital
RECRUITINGFarmington, Connecticut, 06030, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••