Tiny heart device tested in MRI study for common type of heart failure

NCT ID NCT07093528

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study uses a special heart MRI to see if a device called a coronary sinus reducer can improve blood flow in patients with heart failure with preserved ejection fraction (HFpEF) and coronary microvascular dysfunction (small vessel disease). The device is implanted to reroute blood flow in the heart. Researchers will measure changes in blood flow to the inner layer of the heart muscle. The study enrolls 25 adults who are already in a larger trial of the device.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Coronary sinus reducer (a device implanted to improve blood flow in the heart)

What this could lead to

If successful, this could show that the coronary sinus reducer improves blood flow to the heart muscle in patients with heart failure and small vessel disease.

What could go wrong

This is a very small, early substudy (25 people) that only measures changes on MRI. It may not prove any real-world benefit or safety.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

coronary microvascular disorder diastolic heart failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Mayo Clinic

    RECRUITING

    Rochester, Minnesota, 55905, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••