Could a new drug help heart failure patients breathe easier and think sharper?

NCT ID NCT07202000

First seen Nov 01, 2025 · Last updated May 24, 2026 · Updated 26 times

Summary

This study tests whether an investigational drug (activin ligand-trap) combined with exercise training can improve exercise capacity and thinking skills in people with a type of heart failure called HFpEF. About 48 adults aged 40 and older with obesity will receive either the drug or a placebo for 12 weeks. The goal is to see if the drug helps them use oxygen better during exercise and boosts cognitive function.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Massachusetts General Hospital

    Boston, Massachusetts, 02114, United States

Conditions

Explore the condition pages connected to this study.