Can exercise and rehab keep older heart failure patients out of the hospital?
NCT ID NCT05525663
First seen Jun 29, 2026 · Last updated Jul 07, 2026 · Updated 3 times
Summary
This trial tests whether a structured physical rehabilitation and exercise program can help older adults (age 60+) who have been hospitalized for heart failure with preserved ejection fraction (HFpEF). Participants will receive a progressive, multi-domain rehab intervention after discharge. The study measures whether the program reduces the combined risk of rehospitalization and death over six months, and whether it helps prevent major mobility disability, such as the inability to walk a short distance.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- physical rehabilitation and exercise training program
- What this could lead to
- If successful, this program could become a standard approach to help older heart failure patients stay out of the hospital and maintain their ability to walk and live independently.
- What could go wrong
- This is a behavioral intervention, not a drug, so results may vary widely. The study is large but still may not show a clear benefit on hospitalizations or survival.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Atrium Health Wake Forest Baptist
RECRUITINGWinston-Salem, North Carolina, 27157, United States
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