Can short bursts of intense exercise help heart failure patients?

NCT ID NCT04248894

Completed Symptom relief Sponsor: University of Sao Paulo General Hospital Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at whether high-intensity interval training (short bursts of hard exercise) is better than moderate continuous exercise for people with heart failure. Researchers measured nerve activity, blood vessel function, and muscle health in 35 participants. The goal was to see which type of exercise improves the body's ability to control blood flow and daily function.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: exercise training (high-intensity interval training and moderate-intensity continuous training)
What this could lead to: If HIIT proves better, it could offer a more effective exercise program to improve daily function and quality of life for people with heart failure.
What could go wrong: This is a small, completed study with only 35 participants, so results may not apply to all heart failure patients. Exercise programs also require careful supervision to avoid risks.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

heart failure systolic heart failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HEART FAILURE

Contacts and locations

Locations

Heart Institute

São Paulo, Cerqueira Cesar, Brazil
Heart Institute (InCor)

São Paulo, São Paulo, 05403-900, Brazil

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