MRI scans could help decide who needs a heart defibrillator
NCT ID NCT01918215
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether using a heart MRI to find scar tissue can help decide which people with mild-to-moderate heart failure should get a defibrillator (ICD) to prevent sudden cardiac death. About 449 adults with a weakened heart pump (ejection fraction 36-50%) and scar tissue on MRI were randomly assigned to receive an ICD or a small heart monitor. The goal was to see if the ICD group had fewer dangerous heart rhythms or sudden death over three years.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Belfast Health and Social Care Trust
Belfast, BT12 6NT, United Kingdom
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Coburg Hospital
Coburg, 96450, Germany
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Flinders Medical Centre
Bedford Park, South Australia, 5042, Australia
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Glenfield General Hospital
Leicester, LE39QP, United Kingdom
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Golden Jubilee National Hospital
Clydebank, G814DY, United Kingdom
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John Hunter Hospital
New Lambton, New South Wales, 2305, Australia
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Lyell McEwin Hospital
Elizabeth Vale, South Australia, 5112, Australia
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Princess Alexandra Hospital
Brisbane, Queensland, 4102, Australia
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Royal Brisbane & Women's Hospital
Herston, Queensland, 4029, Australia
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Royal Hobart Hospital
Hobart, Tasmania, 7000, Australia
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Royal Perth Hospital
Perth, Western Australia, 6000, Australia
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Schwarzwald-Baar Klinikum
Villingen-Schwenningen, 78052, Germany
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Sir Charles Gairdner Hospital
Nedlands, Western Australia, 6009, Australia
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St Vincent's Hospital
Fitzroy, Victoria, 3065, Australia
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The Alfred
Melbourne, Victoria, 3004, Australia
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The Bristol Heart Institute
Bristol, BS2 8HW, United Kingdom
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University Hospital Wurzburg
Würzburg, 97080, Germany
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University Hospital of South Manchester NHS Foundation Trust
Manchester, M23 9LT, United Kingdom