Could a diaphragm pacemaker help failing hearts?
NCT ID NCT05592392
First seen Jun 24, 2026 · Last updated Jun 26, 2026 · Updated 1 time
Summary
This pilot study tested a device that stimulates the diaphragm in time with the heartbeat to see if it can improve heart function in people with heart failure. 35 participants with reduced ejection fraction received the implant. The study checked for safety and changes in heart size and exercise ability.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Synchronized Diaphragmatic Stimulation (SDS) device
What this could lead to
If it works, this could offer a new way to improve heart function and quality of life for people with heart failure.
What could go wrong
This is a small, early feasibility study with only 35 participants. The device requires surgery and carries risks like infection or breathing problems. Results may not apply to all heart failure patients.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Republican Specialized Scientific and Practical Medical Center for Surgery n.a. V. Vakhidov
Tashkent, 100115, Uzbekistan
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Tbilisi Heart And Vascular Clinic
Tbilisi, 0159, Georgia