Could a cheap rectal pill cut C-Section bleeding?

NCT ID NCT07188207

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tests whether giving a rectal dose of misoprostol before a planned C-section, on top of the usual oxytocin, can reduce blood loss during and after surgery. About 282 women having elective C-sections will be randomly assigned to receive either standard care or standard care plus misoprostol. The goal is to find a simple, low-cost way to prevent dangerous bleeding.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

misoprostol (rectal) plus oxytocin (intravenous)

What this could lead to

If it works, this could offer a cheap, heat-stable way to lower the risk of dangerous bleeding during planned C-sections.

What could go wrong

This is a small, early-stage trial (282 participants) and the added benefit over standard care may be small. Misoprostol can cause side effects like shivering or fever.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Postpartum Hemorrhage

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

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