Less invasive heart repair: device closure offers hope for children with VSD

NCT ID NCT07715032

First seen Jul 20, 2026 · Last updated Jul 21, 2026 · Updated 1 time

Summary

This study looks at how well a device can close a common heart hole called a ventricular septal defect (VSD) in children aged 6 months to 18 years. Instead of open-heart surgery, doctors use a small tube to place a device that plugs the hole. The goal is to see if this method is safe and works well, and to track any problems up to 6 months later.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
a device called an Amplatzer occluder (Ductal, Muscular, or Membranous VSD Occluder) used to close the hole in the heart
What this could lead to
If successful, this could confirm that closing heart holes with a device is a safe, effective alternative to open-heart surgery for children.
What could go wrong
This is a small, short-term study from two centers, so results may not apply broadly. Risks include residual leaks, heart rhythm problems, or device-related issues.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

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