Which sinus surgery technique works best? trial aims to find out
NCT ID NCT07702188
First seen Jul 14, 2026 · Last updated Jul 15, 2026 · Updated 1 time
Summary
This trial compares several endoscopic surgery methods for removing lesions in the sphenoid sinus, a deep cavity behind the nose. About 60 patients with sinus or skull-base lesions will receive one of five surgical approaches. The study measures how completely the lesion is removed and tracks complications such as spinal fluid leak, optic nerve injury, or infection.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- endoscopic sinus surgery (various approaches)
- What this could lead to
- If successful, this could identify the safest and most effective surgical technique for removing sphenoid sinus lesions.
- What could go wrong
- This is a small, single-center surgical trial comparing multiple approaches, so results may not apply broadly. Complications like CSF leak or nerve injury are possible with any sinus surgery.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
About 60 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
-
Aug 2026
An estimate. Start dates often move.
- Expected to finish
-
Sep 2028
An estimate. End dates often move.
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
Children (under 18), adults (18 to 64) and older adults (65 and over)
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients with sinonasal lesions involving sphenid sinus with or without skull base extension. Exclusion Criteria * Severe comorbidities contraindicating surgery * malignant tumer extend beyond sphenoid sinus requiring open management
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Endoscopic sinus surgery are added.
By submitting, you agree to our Terms of use
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
-
The places running it
1 site. The list below names each one and where it is.
-
The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
-
A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
-
Assiut University Hospital
Asyut, Egypt
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can a new anesthetic give surgeons a clearer view during sinus surgery?
- Can knowing frontal sinus anatomy make surgery safer?
- Computer navigation in sinus surgery: a closer look at outcomes
- Scientists to peek inside nose to solve smell loss mystery
- Radical sinus surgery may beat standard for tough nasal polyps