Radical sinus surgery may beat standard for tough nasal polyps
NCT ID NCT04852562
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study compared two types of sinus surgery for people with chronic sinusitis and nasal polyps that involve a type of inflammation called eosinophilic. One surgery (MRESS) removes more tissue, including the middle turbinate, while the standard surgery (FESS) preserves it. The goal was to see if the more radical approach improves quality of life and reduces the need for repeat surgery. 110 Chinese patients were followed for a year after surgery.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
modified radical endoscopic sinus surgery (MRESS)
What this could lead to
If MRESS proves better, it could offer a more effective surgical option for people with stubborn nasal polyps, reducing symptoms and the need for repeat surgery.
What could go wrong
This is a small, single-center study (110 patients) with no blinding. Results may not apply to all patients, and more radical surgery carries higher risks like bleeding or scarring.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Department of ENT, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
Wuhan, Hubei, 430030, China