Radical sinus surgery may beat standard for tough nasal polyps
NCT ID NCT04852562
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study compared two types of sinus surgery for people with chronic sinusitis and nasal polyps that involve a type of inflammation called eosinophilic. One surgery (MRESS) removes more tissue, including the middle turbinate, while the standard surgery (FESS) preserves it. The goal was to see if the more radical approach improves quality of life and reduces the need for repeat surgery. 110 Chinese patients were followed for a year after surgery.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- modified radical endoscopic sinus surgery (MRESS)
- What this could lead to
- If MRESS proves better, it could offer a more effective surgical option for people with stubborn nasal polyps, reducing symptoms and the need for repeat surgery.
- What could go wrong
- This is a small, single-center study (110 patients) with no blinding. Results may not apply to all patients, and more radical surgery carries higher risks like bleeding or scarring.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for CHRONIC SINUSITIS are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Department of ENT, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
Wuhan, Hubei, 430030, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can knowing frontal sinus anatomy make surgery safer?
- Can a drug that calms inflammation ease chronic sinusitis?
- Can an asthma drug shrink nasal polyps? a major trial seeks answers
- Can a single drug shrink nasal polyps and restore breathing?
- Nanoparticle steroid spray could transform recovery after sinus surgery
- Which sinus surgery technique works best? trial aims to find out