Shrimp-Derived nanoparticles take on tough urinary tract infections
NCT ID NCT07482553
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This lab study tests whether chitosan nanoparticles—made from shrimp shells—can break down the sticky biofilms that protect E. coli bacteria in urinary tract infections. Researchers will collect bacteria from 60 patients and treat them with chitosan alone or with the antibiotic ciprofloxacin. They'll also coat urinary catheters with chitosan to see if it prevents biofilm buildup. The goal is to find new ways to fight hard-to-treat UTIs, especially those linked to catheters.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- chitosan nanoparticles
- What this could lead to
- If successful, this could point toward a new way to prevent catheter-related infections and make antibiotics work better against stubborn UTIs.
- What could go wrong
- This is a small, early lab study, not yet tested in people. Results may not translate to real-world use, and chitosan's safety and effectiveness in patients are unknown.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Faculty of Medicine, Assiut University, Microbiology and Immunity department
Asyut, Assiut Governorate, Egypt
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