Nerve-Cutting surgery could replace costly pumps for spasticity
NCT ID NCT07583277
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a surgery called selective dorsal rhizotomy to reduce severe muscle stiffness (spasticity) caused by traumatic brain or spinal cord injury. The surgery involves cutting specific nerve rootlets in the spine to relax overactive muscles. Researchers will enroll 32 people aged 4 and older to see if this one-time procedure works as well as or better than an implanted baclofen pump, which is expensive and requires ongoing maintenance.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Selective dorsal rhizotomy (a surgical procedure that cuts specific nerve rootlets to reduce muscle spasticity)
- What this could lead to
- If successful, this could offer a one-time surgical option to reduce severe muscle stiffness after brain or spinal cord injury, potentially replacing expensive implanted pumps.
- What could go wrong
- This is a small, early-stage study (32 people) with no control group, so results may not apply broadly. Surgery on spinal nerves carries risks of numbness, weakness, or loss of bladder/bowel control.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.